以及男性不育症。
and Male Infertility.
作者信息
Baud David, Vulliemoz Nicolas, Zapata Maria Verónica Morales, Greub Gilbert, Vouga Manon, Stojanov Milos
机构信息
Materno-Fetal and Obstetrics Research Unit, Department Woman-Mother-Child, Lausanne University Hospital, 1011 Lausanne, Switzerland.
Fertility Medicine and Gynaecologic Endocrinology Unit, Department Woman Mother Child, Lausanne University Hospital, 1011 Lausanne, Switzerland.
出版信息
Microorganisms. 2020 Jan 17;8(1):136. doi: 10.3390/microorganisms8010136.
, a -like bacterium, has been previously associated with adverse pregnancy outcomes. Analogously to , also negatively impacts human semen and may be a source of impaired male fertility. In this study, we analyzed seroprevalence in a population of male patients of infertile couples and the impact of past exposition to this bacterium on semen parameters. Our results show a surprisingly high seroprevalence of , which contrasts with a previous study focusing on a population of healthy men. Nevertheless, we did not observe any significant association between positive serology and abnormal sperm parameters. This may suggest that a negative impact on semen is observed only during an ongoing infection. Alternatively, may have an immune impact on male fertility, as previously postulated for women with adverse pregnancy outcomes.
一种α-变形菌此前已被认为与不良妊娠结局有关。与[前文提及的某种菌]类似，[该α-变形菌]也会对人类精液产生负面影响，可能是男性生育能力受损的一个原因。在本研究中，我们分析了不育夫妇中男性患者群体的[该α-变形菌]血清阳性率，以及过去接触这种细菌对精液参数的影响。我们的结果显示[该α-变形菌]的血清阳性率出奇地高，这与之前一项针对健康男性群体的研究形成对比。然而，我们并未观察到血清学阳性与异常精子参数之间存在任何显著关联。这可能表明，只有在持续感染期间才会观察到对精液的负面影响。或者，[该α-变形菌]可能对男性生育能力有免疫影响，正如之前对有不良妊娠结局的女性所假设的那样。
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