中年人群的饮食炎症指数与 S-Klotho 血浆水平。
Dietary Inflammatory Index and S-Klotho Plasma Levels in Middle-Aged Adults.
机构信息
Department of Physiology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
出版信息
Nutrients. 2020 Jan 21;12(2):281. doi: 10.3390/nu12020281.
BACKGROUND
Soluble Klotho (S-Klotho) is an aging suppressor with a close link with inflammation. However, it is still unknown whether the dietary inflammatory potential is associated with S-Klotho plasma level. We aimed to investigate the association of the Dietary Inflammatory Index (DII) with S-Klotho plasma levels in middle-aged sedentary adults.
METHODS
73 middle-aged sedentary adults (40-65 years old) participated in the present study. DII was determined from 28 dietary items obtained by 24 h recalls and food frequency questionnaires. The S-Klotho plasma levels were measured using a solid-phase sandwich enzyme-linked immunosorbent assay.
RESULTS
a weak positive association was observed between DII and S-Klotho plasma levels (β = 52.223, R = 0.057, = 0.043), which disappeared after controlling for body mass index ( = 0.057).
CONCLUSIONS
A pro-inflammatory dietary pattern measured with the DII was slightly and positively associated with S-Klotho plasma levels in middle-aged sedentary adults.
背景
可溶性 Klotho（S-Klotho）是一种与炎症密切相关的衰老抑制剂。然而，饮食炎症指数（DII）与 S-Klotho 血浆水平之间的关系仍不清楚。我们旨在研究中年久坐成年人的 DII 与 S-Klotho 血浆水平之间的关联。
方法
本研究纳入了 73 名中年久坐成年人（40-65 岁）。通过 24 小时回忆和食物频率问卷获得的 28 种饮食项目确定 DII。使用固相夹心酶联免疫吸附测定法测量 S-Klotho 血浆水平。
结果
DII 与 S-Klotho 血浆水平呈弱正相关（β=52.223，R=0.057，=0.043），但在控制体重指数后，这种相关性消失（=0.057）。
结论
DII 测量的促炎饮食模式与中年久坐成年人的 S-Klotho 血浆水平呈轻微正相关。
Zotero 插件