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全身麻醉下双侧颈浅丛阻滞用于甲状腺手术的镇痛效果:一项前瞻性队列研究。

The analgesic efficacy of bilateral superficial cervical plexus block for thyroid surgery under general anesthesia: a prospective cohort study.

作者信息

Woldegerima Yophtahe B, Hailekiros Amare G, Fitiwi Girmay L

机构信息

Department of Anesthesia, College of Medicine and Health Sciences, University of Gondar, Gondar, 196, Ethiopia.

出版信息

BMC Res Notes. 2020 Jan 28;13(1):42. doi: 10.1186/s13104-020-4907-7.

Abstract

OBJECTIVE

Uses of simple analgesics were found insufficient to manage pain after thyroid surgery. We hypothesized that using bilateral superficial cervical plexus block (BSCPB) might influence the pattern of immediate postoperative pain and analgesic consumption. The general objective of the study was to assess the analgesic efficacy of bilateral superficial plexus block for thyroid surgery under general anesthesia.

RESULTS

A total of 74 willing patients involved. Half of them had received BSCPB with 10 ml of 0.25% bupivacaine just before induction and the remaining half did not. Postoperatively, patients were assessed at immediate, 2nd, 6th, 12th and 24th h. At all endpoints, NRS-11 scores for pain were significantly lower in the block group. The time to first analgesic requirement was significantly longer 132.3 ± 71.5 min vs 71.4 ± 60.0 min, p = 0.009. Opioid and total analgesic consumption were reduced by BSCPB in the first 24 postoperative hours. There was low but non-significant rate of PONV in the block group. No clinically important adverse event was noted related to BSCPB. Trial registration The study was registered in Pan African Clinical Trial Registry on 13/01/2020 and the registration number is PACTR202001579588451. Retrospectively registered.

摘要

目的

发现单纯使用镇痛药不足以控制甲状腺手术后的疼痛。我们推测,采用双侧颈浅丛阻滞(BSCPB)可能会影响术后即刻疼痛模式和镇痛药的使用量。本研究的总体目标是评估全身麻醉下双侧颈浅丛阻滞用于甲状腺手术的镇痛效果。

结果

共有74名自愿参与的患者。其中一半在诱导前接受了10毫升0.25%布比卡因的双侧颈浅丛阻滞,另一半未接受。术后,在即刻、第2、6、12和24小时对患者进行评估。在所有观察点,阻滞组的疼痛数字评分量表-11(NRS-11)得分均显著更低。首次需要使用镇痛药的时间显著更长(132.3±71.5分钟对71.4±60.0分钟,p=0.009)。双侧颈浅丛阻滞使术后24小时内的阿片类药物和总镇痛药使用量减少。阻滞组恶心呕吐(PONV)发生率较低但无统计学意义。未观察到与双侧颈浅丛阻滞相关的具有临床重要意义的不良事件。试验注册 本研究于2020年1月13日在泛非临床试验注册中心注册,注册号为PACTR202001579588451。回顾性注册。

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