Tripathi Rakesh Kumar, Verma Yashi, Srivastava Anamika, Shukla Tanu Shree, Usman Kauser, Ali Wahid, Tiwari Sarvada Chandra
Department of Geriatric Mental Health, King George's Medical University, Lucknow, Uttar Pradesh, India.
Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
Indian J Psychiatry. 2020 Jan-Feb;62(1):59-65. doi: 10.4103/psychiatry.IndianJPsychiatry_62_18. Epub 2020 Jan 3.
Clock-drawing test (CDT) is a simple, quick, and bedside cognitive screening test which measures different cognitive domains but has some limitations. The aim of this study was to examine the usefulness of CDT for Indian older adult based on a part of an ICMR-funded research project, New Delhi, India.
Sample comprised seventy participants (38 controls and 32 cases) aged 60 years and above included according to the inclusion/exclusion criteria in a consecutive series. Participants, who gave written informed consent, residing permanently in the area of Chowk, Lucknow, constituted the study sample. Semistructured sociodemographic details and medical history pro forma, socioeconomic status scale, General Health Questionnaire-12 (GHQ-12), CDT, and Hindi cognitive screening test (HCST) were administered. Biochemical investigations were carried out, and blood glucose level (fasting ≤100 mg/dl and postprandial ≤140 mg/dl) was considered for having diabetes mellitus (DM). The participants were categorized into two groups: (1) case: participants with DM only and (2) control: participants without discernible abnormality of physical illness and GHQ negative. Data were analyzed using percentages, -test, the Chi-square test, sensitivity, and specificity.
About 71.05% participants in control and 81.25% in the case group have cognitive impairment on CDT. Significantly higher illiterates ( < 0.05) were found to be significantly more cognitively impaired on HCST. CDT has a high level of sensitivity (0.71) and low specificity (0.23) when compared with HCST.
CDT had screening bias to Indian older adults as a higher number of literates (almost double) and illiterates (four times) were found to be cognitively impaired compared to on HCST. Usefulness of CDT to screen Indian older adults for cognitive impairment is debatable.
画钟试验(CDT)是一种简单、快速的床边认知筛查试验,可测量不同的认知领域,但存在一些局限性。本研究旨在基于印度新德里一项由印度医学研究理事会资助的研究项目的一部分,探讨CDT对印度老年人的实用性。
样本包括70名年龄在60岁及以上的参与者(38名对照组和32名病例组),根据纳入/排除标准连续纳入。签署书面知情同意书、永久居住在勒克瑙乔克地区的参与者构成研究样本。进行了半结构化的社会人口学详细信息和病史表格、社会经济地位量表、一般健康问卷-12(GHQ-12)、CDT和印地语认知筛查试验(HCST)。进行了生化检查,空腹血糖水平≤100mg/dl且餐后血糖水平≤140mg/dl被视为患有糖尿病(DM)。参与者被分为两组:(1)病例组:仅患有DM的参与者;(2)对照组:身体疾病无明显异常且GHQ阴性的参与者。使用百分比、t检验、卡方检验、敏感性和特异性对数据进行分析。
对照组约71.05%的参与者和病例组81.25%的参与者在CDT上存在认知障碍。发现文盲在HCST上的认知障碍明显更高(P<0.05)。与HCST相比,CDT具有较高的敏感性(0.71)和较低的特异性(0.23)。
CDT对印度老年人存在筛查偏差,因为与HCST相比,发现识字者(几乎翻倍)和文盲(四倍)的认知障碍人数更多。CDT用于筛查印度老年人认知障碍的实用性值得怀疑。