The David J. Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany.
PLoS One. 2020 Feb 4;15(2):e0228342. doi: 10.1371/journal.pone.0228342. eCollection 2020.
Ray propagation visualization and optical performance analysis of four different intraocular lenses (IOLs).
In this laboratory study, four IOLs with different optical designs were assessed: a monofocal AcrySof IQ SN60WF [Alcon], a diffractive-refractive bifocal AcrySof IQ Restor SN6AD1 [Alcon], a diffractive trifocal AcrySof IQ PanOptix TFNT00 [Alcon], and a diffractive extended-depth-of-focus (EDOF) Symfony ZXR00 [Johnson&Johnson]. An experimental set-up with a water bath containing 0.01% fluorescein solution and monochromatic green laser light (532 nm) was used to visualize the propagation of light rays. Also, the optical performance of the IOLs was evaluated by measuring the modulation transfer function (MTF) values at a pupil sizes of 3.0 and 4.5 mm on the optical bench OptiSpheric® IOL PRO II (Trioptics GmbH, Germany).
Both the diffractive-refractive bifocal IOL and the EDOF IOL showed two defined foci for distance and near vision. In the diffractive trifocal IOL, three distinct foci for distance, intermediate, and near vision could be visualized.
The ray propagation visualization technique allows a qualitative assessment and comparison of light energy distribution between different IOL models. The measured Through-Focus Response (TFR) quantitatively confirmed the evaluated ray propagation behavior.
可视化四种不同人工晶状体(IOL)的光线传播和光学性能分析。
在这项实验室研究中,评估了四种具有不同光学设计的 IOL:单焦点 AcrySof IQ SN60WF [Alcon]、衍射折射双焦点 AcrySof IQ Restor SN6AD1 [Alcon]、衍射三焦点 AcrySof IQ PanOptix TFNT00 [Alcon]和衍射扩展景深(EDOF)Symfony ZXR00 [Johnson&Johnson]。使用一个包含 0.01%荧光素溶液和单色绿光(532nm)的水浴实验装置来可视化光线的传播。此外,通过在光学基准台上测量调制传递函数(MTF)值,评估了 IOL 的光学性能OptiSpheric® IOL PRO II(Trioptics GmbH,德国)在瞳孔尺寸为 3.0 和 4.5mm 时。
衍射折射双焦点 IOL 和 EDOF IOL 均显示出用于远距离和近距离视力的两个定义焦点。在衍射三焦点 IOL 中,可以看到用于远距离、中间距离和近距离视力的三个明显焦点。
光线传播可视化技术允许对不同 IOL 模型之间的光能分布进行定性评估和比较。测量的 Through-Focus Response(TFR)定量证实了评估的光线传播行为。