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炎症性肠病中抗肿瘤坏死因子药物的生物类似药

Biosimilars to Antitumor Necrosis Factor Agents in Inflammatory Bowel Disease.

作者信息

Al Sulais Eman, AlAmeel Turki

机构信息

Department of Medicine, Royal Commission Hospital, Jubail, Saudi Arabia.

Department of Medicine, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

出版信息

Biologics. 2020 Jan 10;14:1-11. doi: 10.2147/BTT.S236433. eCollection 2020.

Abstract

Anti- tumor Necrosis Factor (anti-TNF) agents are the backbone treatment of moderate to severe cases of inflammatory bowel disease. One of the main drawbacks of these agents is the high cost. The introduction of biosimilar products to anti-TNF agents is expected to lower the cost. Health care providers ought to be aware of the available data that addresses the safety and efficacy of biosimilars in IBD patients. This article outlines the current evidence-based data regarding the available biosimilar products, their safety, efficacy and how to deal with patients' concerns.

摘要

抗肿瘤坏死因子(抗TNF)药物是中重度炎症性肠病的主要治疗药物。这些药物的主要缺点之一是成本高昂。预计抗TNF生物类似药的推出将降低成本。医疗服务提供者应该了解有关生物类似药在炎症性肠病患者中的安全性和有效性的现有数据。本文概述了有关现有生物类似药产品、其安全性、有效性以及如何处理患者担忧的当前循证数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a91f/6966952/1a4b3fbf958e/BTT-14-1-g0001.jpg

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