具有品行问题的青少年在风险决策时的行为和神经差异特征。
Differential Behavioral and Neural Profiles in Youth With Conduct Problems During Risky Decision-Making.
机构信息
University of North Carolina at Chapel Hill.
Washington University at Saint Louis.
出版信息
J Res Adolesc. 2020 Sep;30(3):599-615. doi: 10.1111/jora.12546. Epub 2020 Feb 7.
Neuroimaging work has examined neural processes underlying risk taking in adolescence, yet predominantly in low-risk youth. To determine whether we can extrapolate from current neurobiological models, this functional magnetic resonance imaging study investigated risk taking and peer effects in youth with conduct problems (CP; N = 19) and typically developing youth (TD; N = 25). Results revealed higher real-life risk taking, lower risky decisions, and no peer effects on a risk-taking task in CP youth. CP youth showed greater ventral striatum (VS) activity during safe than risky decisions, whereas TD youth showed greater VS activation during risky decisions. Differential VS activity explained higher real-life risk taking in CP youth. Findings provide preliminary evidence that risk-taking behavior in youth with CD problems is characterized by differential neural patterns.
神经影像学研究已经考察了青少年冒险行为的神经过程，但主要是在低风险的青少年中。为了确定我们是否可以从当前的神经生物学模型推断，这项功能磁共振成像研究调查了具有行为问题（CP；N=19）和典型发育的青少年（TD；N=25）的冒险行为和同伴效应。结果显示，CP 青少年的现实生活中的冒险行为更高，冒险决策更低，风险任务上没有同伴效应。CP 青少年在安全决策时表现出更大的腹侧纹状体（VS）活动，而 TD 青少年在冒险决策时表现出更大的 VS 激活。VS 活动的差异解释了 CP 青少年更高的现实生活中的冒险行为。研究结果初步表明，患有 CD 问题的青少年的冒险行为具有不同的神经模式。
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