Department of Pediatric Cardiovascular Surgery, Okinawa Prefectural Nanbu Medical Center and Children's Medical Center, Arakawa 118-1, Haebaru-cho, Okinawa, 901-1193, Japan.
Department of Clinical Engineering, Okinawa Prefectural Nanbu Medical Center and Children's Medical Center, Arakawa 118-1, Haebaru-cho, Okinawa, 901-1193, Japan.
Gen Thorac Cardiovasc Surg. 2020 Sep;68(9):956-961. doi: 10.1007/s11748-020-01304-7. Epub 2020 Feb 7.
We evaluated beating heart thoracic aortic surgery (BHTAS) using selective myocardial perfusion (SMP) in patients with aortic anomalies with complex surgical needs.
Between 2012 and 2018, 27 infants with aortic anomalies underwent BHTAS using SMP.
Median body weight was 3.5 kg (range 2.6-5.2). In total, 15 cases of aortic coarctation, 7 cases of hypoplastic left heart syndrome, and 5 cases of interrupted aortic arch were included. An extended aortic arch anastomosis maneuver was used in 7 cases and aortic arch reconstruction compensated with an autologous pericardium patch was used in 6 cases. A Norwood-type procedure was used in 11 cases. The median Aristotle comprehensive score was 13.9 (7.0-20.0). BHTAS cases were not inferior in postoperative CK-MB/CK ratio (12.4 ± 2.8 in BHTAS vs 13.9 ± 3.6 in CTAS, p = 0.09), and there were no instances of myocardial ischemia. Two late deaths occurred due to shunt obstruction (n = 1) and valve malfunction (n = 1). Freedom from aortic reintervention was not inferior to conventional thoracic aortic surgery. BHTAS cases exhibited shorter cardiac arrest time than that of conventional thoracic aortic surgery in similar surgical procedures [CoA/VSD cases: 48.0 ± 8.0 min in the BHTAS cases and 65.7 ± 10.8 min in the CTAS cases (p = 0.0122), simple CoA/re-CoA cases: 0 min in the BHTAS cases and 20.1 ± 3.6 min in the CTAS cases].
BHTAS reduced cardioplegic arrest time while maintaining postoperative CK-MB/CK ratio, mid-term death, and aortic reintervention rates.
我们评估了使用选择性心肌灌注(SMP)的心脏不停跳胸主动脉手术(BHTAS)在具有复杂手术需求的主动脉畸形患者中的应用。
2012 年至 2018 年,27 例主动脉畸形患者接受了 BHTAS 联合 SMP。
中位体重为 3.5kg(范围 2.6-5.2kg)。共有 15 例主动脉缩窄、7 例左心发育不全综合征和 5 例主动脉弓中断患者。7 例采用扩展主动脉弓吻合术,6 例采用自体心包片行主动脉弓重建。11 例患者采用 Norwood 手术。Aristotle 综合评分中位数为 13.9(7.0-20.0)。BHTAS 组术后 CK-MB/CK 比值(BHTAS 组 12.4±2.8,CTAS 组 13.9±3.6,p=0.09)不劣于传统的胸主动脉手术,且无心肌缺血。2 例患者分别因分流阻塞(n=1)和瓣膜功能障碍(n=1)而死亡。BHTAS 组与传统胸主动脉手术相比,主动脉再次干预率无差异。对于相似的手术,BHTAS 组的心脏停搏时间短于传统的胸主动脉手术[CoA/VSD 病例:BHTAS 组 48.0±8.0min,CTAS 组 65.7±10.8min(p=0.0122);单纯 CoA/re-CoA 病例:BHTAS 组 0min,CTAS 组 20.1±3.6min]。
BHTAS 在维持术后 CK-MB/CK 比值、中期死亡率和主动脉再次干预率的同时,减少了停搏时间。