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迟发性巨细胞病毒病在肝移植受者中表现为结肠狭窄。

Late onset CMV disease presenting as a colonic stricture in a liver transplant recipient.

作者信息

Zeidan Joseph H, Kamionek Michal, Noell Bennett C, Schmeltzer Paul A, deLemos Andrew S, Gajurel Kiran

机构信息

Division of Gastroenterology and Hepatology, Carolinas Medical Center, Atrium Health, Charlotte, NC, USA.

Carolinas Pathology Group, Charlotte, NC, USA.

出版信息

Transpl Infect Dis. 2020 Apr;22(2):e13259. doi: 10.1111/tid.13259. Epub 2020 Feb 24.

Abstract

Cytomegalovirus (CMV) is a common opportunistic infection in solid organ transplant (SOT) recipients in the first 6 months after transplant. Late onset CMV infection or disease outside the classical risk period is uncommon and can present with atypical signs and symptoms. Here, we report a case of late onset CMV presenting as a colonic stricture more than 10 years after liver transplantation in the absence of traditional CMV risk factors. We also briefly review CMV colitis presenting as a mass or stricture in SOT recipients.

摘要

巨细胞病毒(CMV)是实体器官移植(SOT)受者在移植后最初6个月内常见的机会性感染。在经典风险期之外发生的迟发性CMV感染或疾病并不常见,可能表现为非典型的体征和症状。在此,我们报告一例肝移植10多年后出现结肠狭窄的迟发性CMV病例,该病例不存在传统的CMV风险因素。我们还简要回顾了SOT受者中表现为肿块或狭窄的CMV结肠炎。

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