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经斜坡入路切除脑桥海绵状血管瘤:二维手术视频

Transclival Approach for Resection of a Pontine Cavernous Malformation: 2-Dimensional Operative Video.

作者信息

London Dennis, Lieberman Seth, Tanweer Omar, Pacione Donato

机构信息

Department of Neurosurgery, NYU Langone Health, New York, New York.

Department of Otolaryngology, NYU Langone Health, New York, New York.

出版信息

Oper Neurosurg (Hagerstown). 2020 Sep 15;19(4):E413. doi: 10.1093/ons/opaa025.

Abstract

Cerebral cavernous malformations are common vascular anomalies consisting of a cluster of capillaries without intervening brain tissue.1 A variety of approaches for resection have been undertaken,2 and a handful of case reports have described the endoscopic, endonasal, transclival approach.3 We present a case of a 51-yr-old woman with lupus and hepatitis B-associated cirrhosis who presented with diplopia, dysphagia, and ataxia. She had a left abducens nerve palsy and magnetic resonance imaging (MRI) showed a left pontine cavernous malformation. After a repeat hemorrhage, she consented to surgical resection. The lesion appeared to come to the medial pontine pial surface. Tractography indicated a rightward displacement of the left corticospinal tract. Therefore, an endoscopic, transnasal, transclival approach was chosen. A lumbar drain was placed preoperatively. The clivus and ventral petrous bone were drilled using the vidian canal to help identify the anterior genu of the petrous carotid artery. The clival dura was opened, revealing the abducens nerve exiting the ventral pons. The cavernoma was visible on the surface lateral to the nerve. It was removed using blunt dissection and the remaining cavity inspected. The skull base was reconstructed using an abdominal dermal-fat graft and Alloderm covered by a nasoseptal flap. Postoperatively she had transient swallowing difficulty. The lumbar drain was kept open for 5 d. Cerebrospinal fluid (CSF) leak was ruled out using an intrathecal fluorescein injection. She was discharged home, but presented 2 wk postoperatively with aseptic meningitis, which was treated supportively. Postoperative imaging did not show residual cavernoma.

摘要

脑海绵状血管畸形是常见的血管异常,由一簇无中间脑组织的毛细血管组成。已经采用了多种切除方法,并且有少数病例报告描述了内镜下经鼻经斜坡入路。我们报告一例51岁患有狼疮和乙型肝炎相关性肝硬化的女性,她出现复视、吞咽困难和共济失调。她有左侧展神经麻痹,磁共振成像(MRI)显示左侧脑桥海绵状血管畸形。再次出血后,她同意手术切除。病变似乎位于脑桥内侧软膜表面。神经束成像显示左侧皮质脊髓束向右移位。因此,选择了内镜下经鼻经斜坡入路。术前放置了腰大池引流管。使用翼管对斜坡和岩骨腹侧进行钻孔,以帮助识别岩骨颈动脉的前膝部。打开斜坡硬脑膜,露出从脑桥腹侧发出的展神经。在神经外侧表面可见海绵状血管瘤。采用钝性分离将其切除,并检查剩余腔隙。使用腹部真皮脂肪移植和鼻中隔瓣覆盖的同种异体真皮重建颅底。术后她出现短暂的吞咽困难。腰大池引流管开放5天。通过鞘内注射荧光素排除脑脊液漏。她出院回家,但术后2周出现无菌性脑膜炎,给予支持治疗。术后影像学检查未显示残留的海绵状血管瘤。

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