Taizhou People's Hospital, 366 Taihu Road, Taizhou, 225300, Jiangsu, China.
The Fifth Affiliated Hospital of Nantong University, Taizhou, 225300, Jiangsu, China.
Arch Virol. 2020 Apr;165(4):955-958. doi: 10.1007/s00705-020-04549-y. Epub 2020 Feb 11.
Sapoviruses (SAVs), including several genogroups (GI to GV), are one of the causes of acute gastroenteritis (AGE). In this study, viral metagenomics revealed the presence of sapoviruses of different genogroups in stool from children with AGE. Eight different complete SAV genomes were determined, of which five belonged to GI and the other three belonged to GII, GIV and GV, respectively. Although they were highly similar to published sequences, the GIV and GV were the first complete genome sequences of these SAVs found in China. In a prevalence investigation, 19% of subjects with AGE were positive for SAVs, while none of the control group was positive.
肠型诺如病毒（Sapoviruses，SAVs）包括多个基因群（GI 到 GV），是引起急性肠胃炎（Acute Gastroenteritis，AGE）的原因之一。本研究通过病毒宏基因组学方法，在 AGE 患儿粪便中发现了不同基因群的肠型诺如病毒。共确定了 8 株不同的完整 SAV 基因组，其中 5 株属于 GI，另外 3 株分别属于 GII、GIV 和 GV。尽管它们与已发表的序列高度相似，但 GIV 和 GV 是首次在中国发现的这两种 SAV 的完整基因组序列。在流行情况调查中，19%的 AGE 患儿 SAV 阳性，而对照组均为阴性。
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