运动、大脑训练和讲座计划预防认知能力下降。
A program of exercise, brain training, and lecture to prevent cognitive decline.
机构信息
Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University, 86, Nishi-cho, Yonago, 683-8503, Japan.
Division of Medical Science in Sports and Exercise, Department of Social Medicine, Faculty of Medicine, Tottori University, 4-101 Koyama-cho Minami, Tottori, 680-8550, Japan.
出版信息
Ann Clin Transl Neurol. 2020 Mar;7(3):318-328. doi: 10.1002/acn3.50993. Epub 2020 Feb 18.
OBJECTIVE
We examined the benefits of a community-based program combining physical exercise, cognitive training, and education on dementia and lifestyle habits.
METHODS
This crossover open-label trial included 141 community-dwelling elderly people with suspected mild cognitive decline (MCD). Subjects were assigned to a 6-month intervention-first/6-month observation-second (INT-OBS) group or an OBS-INT group. The 6-month intervention consisted of 2 h of physical exercise, cognitive training, and classroom study or rest once weekly. Primary outcome was change in Touch Panel-type Dementia Assessment Scale (TDAS) score.
RESULTS
TDAS score improved significantly during the intervention period compared with the observation period for all subjects (P < 0.05). Some physical functions also improved significantly during the intervention period compared with the observation period in the OBS-INT group (P < 0.05).
INTERPRETATION
This community-based program improved both cognitive and physical function in elderly people with suspected MCD.
目的
我们研究了将身体锻炼、认知训练和教育结合在一起的社区项目对痴呆症和生活方式习惯的益处。
方法
这是一项交叉开放标签试验，纳入了 141 名有疑似轻度认知障碍（MCD）的社区居住的老年人。受试者被分配到干预第一/观察第二（INT-OBS）组或观察第一/干预第二（OBS-INT）组。6 个月的干预包括每周 1 次的 2 小时身体锻炼、认知训练和课堂学习或休息。主要结局是 Touch Panel 型痴呆评估量表（TDAS）评分的变化。
结果
与观察期相比，所有受试者在干预期 TDAS 评分显著改善（P<0.05）。与观察期相比，OBS-INT 组在干预期的一些身体功能也显著改善（P<0.05）。
结论
该基于社区的项目改善了疑似 MCD 老年人的认知和身体功能。
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