在血友病和克里斯马斯病血尿治疗中使用与不使用泼尼松龙进行凝血因子替代治疗的比较。
A comparison of coagulation factor replacement with and without prednisolone in the treatment of haematuria in haemophilia and Christmas disease.
作者信息
Rizza C R, Kernoff P B, Matthews J M, McLennan C R, Rainsford S G
出版信息
Thromb Haemost. 1977 Feb 28;37(1):86-90.
PMID:320712
Abstract
A double-blind controlled study was carried out to investigate the effectiveness of treatment with factor VIII or factor IX concentrate and a reducing dose of prednisolone in contolling haematuria in patients with haemophilia and Christmas disease. 41 episodes of haematuria were studied in 30 different patients. No appreciable benefit was observed in the treated, as compared with the control group and this is at variance with the results of the few studies reported elsewhere.
摘要
开展了一项双盲对照研究，以调查使用凝血因子VIII或凝血因子IX浓缩物以及递减剂量泼尼松龙治疗对控制血友病和克里斯马斯病患者血尿的有效性。对30名不同患者的41次血尿发作进行了研究。与对照组相比，治疗组未观察到明显益处，这与其他地方报道的少数研究结果不一致。
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