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南非豪登省和西北省靠近金矿堆的社区老年人中的非过敏性鼻炎和相关危险因素:一项横断面研究。

Non-allergic rhinitis and associated risk factors among the elderly in communities close to gold mine dumps in Gauteng and North West provinces in South Africa: a cross-sectional study.

机构信息

Environment and Health Research Unit, South African Medical Research Council, Johannesburg, 2094, South Africa.

School of Health Systems and Public Health, Faculty of Health Sciences, University of Pretoria, Pretoria, 0001, South Africa.

出版信息

Int Arch Occup Environ Health. 2020 Aug;93(6):715-721. doi: 10.1007/s00420-020-01526-5. Epub 2020 Feb 18.

Abstract

PURPOSE

To investigate whether non-allergic rhinitis among the elderly was associated with living close to mine dumps METHODS: Elderly persons (n = 2397) residing in communities 1-2 km (exposed) and ≥ 5 km (unexposed) from five preselected mine dumps in Gauteng and North West provinces in South Africa were included in the cross-sectional study, using a previously validated modified ATS-DLD-78 questionnaire from the British Medical Research Council.

RESULTS

The overall prevalence of non-allergic rhinitis in this study was 23.99%. In the unexposed, it was found to be 18.82% and 27.08% exposed communities. Multiple logistic regression analysis indicated that having non-allergic rhinitis was significantly associated with living in exposed communities (OR 1.73; 95% CI 1.37-2.17), being an ex-smoker (OR 1.75; 95 CI 1.35-2.26), being a smoker (OR 1.24; 95% CI 1.02-1.62), history of occupational exposure to dust/chemical fumes (OR 1.58; 1.30-1.93) and use of gas as the main residential heating/cooking fuel type (OR 1.61; 1.01-2.57).

CONCLUSION

A high prevalence of non-allergic rhinitis was observed in the elderly living in exposed communities. The adverse association was observed between residing in communities close to mine dumps and non-allergic rhinitis.

摘要

目的

研究老年人非过敏性鼻炎是否与居住在矿山附近有关。

方法

本横断面研究纳入了居住在南非豪登省和西北省五个预选矿山附近 1-2 公里(暴露组)和≥5 公里(非暴露组)社区的 2397 名老年人,使用了英国医学研究委员会先前验证过的改良 ATS-DLD-78 问卷。

结果

本研究中非过敏性鼻炎的总患病率为 23.99%。在非暴露组中,患病率为 18.82%,而在暴露组中为 27.08%。多因素逻辑回归分析表明,居住在暴露组与非过敏性鼻炎显著相关(OR 1.73;95%CI 1.37-2.17),与曾吸烟者(OR 1.75;95%CI 1.35-2.26)、吸烟者(OR 1.24;95%CI 1.02-1.62)、职业性接触粉尘/化学烟雾史(OR 1.58;1.30-1.93)和使用煤气作为主要居住加热/烹饪燃料类型(OR 1.61;1.01-2.57)有关。

结论

暴露组中老年人非过敏性鼻炎的患病率较高。居住在矿山附近社区与非过敏性鼻炎之间存在不良关联。

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