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急性A型主动脉夹层冰冻象鼻手术的早期和中期结果

Early and mid-term results of frozen elephant trunk procedure for acute type A aortic dissection.

作者信息

Akbulut Mustafa, Ak Adnan, Arslan Özgür, Çekmecelioğlu Davut, Taş Serpil, Antal Dönmez Arzu, Şişmanoğlu Mesut, Tuncer Mehmet Altuğ

机构信息

Department of Cardiovascular Surgery, Kartal Koşuyolu Yüksek İhtisas Training and Research Hospital, İstanbul, Turkey.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2019 Mar 24;27(2):135-142. doi: 10.5606/tgkdc.dergisi.2019.16879. eCollection 2019 Apr.

Abstract

BACKGROUND

This study aims to investigate the early and mid-term results of total thoracic aorta repair with E-vita OPEN PLUS stent graft, which we used to remove the residual false lumen and prevent late-term complications in patients with acute type A aortic dissections.

METHODS

The study included 41 patients (29 males, 12 females; mean age 51.9±10.4 years; range, 30 to 77 years) who underwent total thoracic aorta repair with frozen elephant trunk stent graft for acute type A aortic dissection between November 2013 and November 2017. The reduction in false lumen size and thrombosis were evaluated by repeated computed tomographyangiography on 10th day and third, sixth, and 12th months.

RESULTS

Six patients (14.6%) were lost during hospital stay and one patient (2.4%) was lost during the follow-up period. Frozen elephant trunk stent graft"s distal end at descending aorta ended at T, T, and T levels in 15 (36.6%), 21 (51.2%), and five (12.2%) patients, respectively. The supra-aortic vessels were re-implanted separately in 21 (51.2%) or as island in 20 (48.8%) patients. Transient paraparesis (spinal cord ischemia) was observed in only one patient (2.4%), while permanent neurologic deficit (stroke or coma) was observed in two patients (4.9%). Mean duration of follow-up was 26.5±20.5 months. Computed tomography-angiography at first month showed that false lumen became thrombosed at rates of 93.9% and 54.5% at pulmonary trunk and diaphragmatic level, respectively.

CONCLUSION

We believe that total arcus repair in acute type A aortic dissection treatment with single-session frozen elephant trunk technique by ensuring early false lumen thrombosis is safe and successful.

摘要

背景

本研究旨在探讨使用E-vita OPEN PLUS支架型人工血管进行全胸主动脉修复的早期和中期结果,我们使用该支架型人工血管来消除急性A型主动脉夹层患者的残余假腔并预防晚期并发症。

方法

本研究纳入了41例患者(29例男性,12例女性;平均年龄51.9±10.4岁;范围30至77岁),这些患者在2013年11月至2017年11月期间接受了冷冻象鼻支架型人工血管全胸主动脉修复术治疗急性A型主动脉夹层。在术后第10天以及第3、6和12个月通过重复计算机断层扫描血管造影术评估假腔大小的缩小和血栓形成情况。

结果

6例患者(14.6%)在住院期间死亡,1例患者(2.4%)在随访期间死亡。冷冻象鼻支架型人工血管在降主动脉的远端分别终止于T、T和T水平,患者分别为15例(36.6%)、21例(51.2%)和5例(12.2%)。21例(51.2%)患者的主动脉弓上血管分别进行了再植入,20例(48.8%)患者的主动脉弓上血管作为岛状进行了再植入。仅1例患者(2.4%)出现短暂性截瘫(脊髓缺血),2例患者(4.9%)出现永久性神经功能缺损(中风或昏迷)。平均随访时间为26.5±20.5个月。术后第1个月的计算机断层扫描血管造影显示,在肺动脉干和膈肌水平,假腔血栓形成率分别为93.9%和54.5%。

结论

我们认为,通过确保早期假腔血栓形成,采用单期冷冻象鼻技术治疗急性A型主动脉夹层的全弓修复是安全且成功的。

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