Iqbal Hamid, Tameez Ud Din Asma, Tameez Ud Din Asim, Chaudhary Farooq Mohyud Din, Younas Muhammad, Jamil Abdur
Hematology, Combined Military Hospital Multan, Multan, PAK.
Internal Medicine, Rawalpindi Medical University, Rawalpindi, PAK.
Cureus. 2020 Jan 14;12(1):e6657. doi: 10.7759/cureus.6657.
Background & Aim It is of great importance to carefully choose appropriate donors according to strict eligibility criteria, so as to guarantee an adequate and safe blood supply. The aim of this study was to determine the rate of deferral in blood donors and evaluate the different causes of deferral in Multan. Materials & Methods This prospective study was carried out at the Blood Bank of Combined Military Hospital (CMH) Multan. All donors who came for the donation of blood from 1st February to 30th September 2019 were evaluated after taking their consent. The data was analyzed to determine the frequency and causes of deferral using Statistical Package for the Social Sciences (SPSS) version 20. Results Among 3348 individuals presenting for blood donation, 433 (12.9%) were deferred (427 males and only six females). The mean age of deferred individuals was 28.96 + 6.42 years. The youngest individual was 18 years, while the eldest one was 51 years of age. Almost 65% of the individuals were less than 30 years of age. The most frequent cause of deferral was low hemoglobin. Anemia was the leading cause of deferral in more than half of the individuals (= 221). Hepatitis C virus (HCV) infection was the second most frequent cause of deferral, seen in 83 (19.2%), followed by hepatitis B virus (HBV) infection (= 49, 11.3%), syphilis (= 36, 8.3%), thrombocytopenia (= 18, 4.2%), and active infection (= 14, 3.2%). Other rarer causes included early donation, thrombocytosis, polycythemia, pancytopenia, malaria, allergies, insulin, and tuberculosis. Conclusion Deferral for blood donation is a significant problem in Multan and accounts for almost 13% of all prospective blood donors. Our results stress the importance of addressing the problem of anemia which is the most prevalent cause of temporary deferral for blood donation in this region of the world.
背景与目的 根据严格的合格标准谨慎选择合适的献血者至关重要,以确保充足且安全的血液供应。本研究的目的是确定木尔坦地区献血者的延期率,并评估延期的不同原因。材料与方法 本前瞻性研究在木尔坦联合军事医院(CMH)血库进行。2019年2月1日至9月30日前来献血的所有献血者在获得其同意后进行评估。使用社会科学统计软件包(SPSS)20版对数据进行分析,以确定延期的频率和原因。结果 在3348名前来献血的个体中,433人(12.9%)被延期(427名男性,仅6名女性)。延期个体的平均年龄为28.96±6.42岁。最年轻的个体为18岁,最年长的为51岁。几乎65%的个体年龄小于30岁。延期最常见的原因是血红蛋白水平低。贫血是超过一半个体(=221)延期的主要原因。丙型肝炎病毒(HCV)感染是延期的第二大常见原因,有83人(19.2%),其次是乙型肝炎病毒(HBV)感染(=49人,11.3%)、梅毒(=36人,8.3%)、血小板减少症(=18人,4.2%)和活动性感染(=14人,3.2%)。其他较罕见的原因包括过早献血、血小板增多症、红细胞增多症、全血细胞减少症、疟疾、过敏、胰岛素和结核病。结论 在木尔坦,献血延期是一个重大问题,占所有潜在献血者的近13%。我们的结果强调了解决贫血问题的重要性,贫血是世界该地区献血临时延期最普遍的原因。