Paul Strickland Scanner Centre, Northwood, England.
Imaging Department, Imperial College Healthcare NHS Trust, London, United Kingdom.
Br J Radiol. 2020 Jul;93(1111):20190832. doi: 10.1259/bjr.20190832. Epub 2020 Feb 27.
F-Fluorodeoxyglucose positron emission tomography/CT imaging plays a key role in oncological imaging including in staging, radiotherapy planning, treatment response and recurrence assessment. Immunotherapies represent a major advance in cancer therapy for a number of tumours with resulting survival benefit. However, a wide range of immune related adverse events (irAEs), some of which can be apparent on imaging, have been reported. These involve many organ systems but particularly endocrine, cutaneous and gastrointestinal systems. Early detection of irAEs is essential to aid diagnosis and management of patients and to reduce associated morbidity. In addition, it is important to not mistake treatment related effects for disease.This pictorial review aims to identify common irAEs and changes seen on F-fluorodeoxyglucose positron emission tomography/CT.
氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描成像在肿瘤学成像中起着关键作用,包括分期、放射治疗计划、治疗反应和复发评估。免疫疗法代表了许多肿瘤治疗的重大进展,带来了生存获益。然而,已经报道了广泛的免疫相关不良事件(irAEs),其中一些在影像学上可以表现出来。这些涉及许多器官系统,但特别是内分泌、皮肤和胃肠道系统。早期发现 irAEs 对于帮助诊断和管理患者以及减少相关发病率至关重要。此外,重要的是不要将治疗相关的影响误认为是疾病。本影像学综述旨在确定氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描上常见的 irAEs 和变化。