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[婴儿利什曼原虫引起的舌下假瘤样利什曼病]

[Pseudotumoral sublingual leishmaniasis caused by Leishmaniainfantum].

作者信息

Hocar O, Aboudourib M, Akhdari N, Hamdaoui A, Mouttaki T, Soussi M, Chiheb S, Amal S, Riyad M

机构信息

Service de dermatologie, CHU Mohammed VI, faculté de médecine, université Cadi Ayyad, Marrakech, Maroc.

Service de dermatologie, CHU Mohammed VI, faculté de médecine, université Cadi Ayyad, Marrakech, Maroc.

出版信息

Ann Dermatol Venereol. 2020 May;147(5):383-386. doi: 10.1016/j.annder.2020.01.011. Epub 2020 Feb 24.

Abstract

INTRODUCTION

Mucosal leishmaniasis is endemic in certain parts of Latin America and are usually absent in Morocco. Herein we report a case of Leishmaniainfantum in a Moroccan patient.

PATIENTS AND METHODS

A 61-year-old male patient working as a tourist bus driver presented with a sublingual endobuccal tumor. He reported a history of treated cutaneous leishmaniasis of the lower lip in 2009 and had presented the sublingual oral tumor since December 2011. The histopathological findings as well as the species-specific PCR analysis confirmed the diagnosis of sublingual mucosal leishmaniasis due to L. infantum. HIV serology was negative. Our patient was then treated with intra-muscular meglumine antimoniate for 25 days, resulting in complete disappearance of the oral lesion.

CONCLUSION

Our case thus has several peculiarities: the strictly mucosal character of the lesion, occurring in an immunocompetent subject, the unusual pseudotumoral form, and the causative agent, L. infantum, not known for its mucosal tropism in our country.

摘要

引言

黏膜利什曼病在拉丁美洲的某些地区为地方病,在摩洛哥通常不存在。在此,我们报告一例摩洛哥患者的婴儿利什曼原虫病病例。

患者与方法

一名61岁男性患者,职业为旅游巴士司机,出现舌下口腔内肿瘤。他报告有2009年下唇皮肤利什曼病治疗史,自2011年12月起出现舌下口腔肿瘤。组织病理学检查结果以及种特异性聚合酶链反应分析证实诊断为婴儿利什曼原虫引起的舌下黏膜利什曼病。艾滋病毒血清学检查为阴性。然后,我们的患者接受了25天的肌肉注射葡甲胺锑酸盐治疗,口腔病变完全消失。

结论

因此,我们的病例有几个特点:病变严格局限于黏膜,发生在免疫功能正常的个体,呈现不寻常的假瘤形式,以及病原体婴儿利什曼原虫,在我国并不以其黏膜嗜性而闻名。

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