Faculty of Applied Sciences, UCSI University, 56000 Cheras, Kuala Lumpur, Malaysia.
School of Foundation Studies, Xiamen University Malaysia, 43900 Sepang, Selangor, Malaysia.
J Integr Med. 2020 May;18(3):189-195. doi: 10.1016/j.joim.2020.02.006. Epub 2020 Feb 20.
Flavonoids are by far the most dominant class of phenolic compounds isolated from Morus alba leaves (MAL). Other classes of compounds are benzofurans, phenolic acids, alkaloids, coumarins, chalcones and stilbenes. Major flavonoids are kuwanons, moracinflavans, moragrols and morkotins. Other major compounds include moracins (benzofurans), caffeoylquinic acids (phenolic acids) and morachalcones (chalcones). Research on the anticancer properties of MAL entailed in vitro and in vivo cytotoxicity of extracts or isolated compounds. Flavonoids, benzofurans, chalcones and alkaloids are classes of compounds from MAL that have been found to be cytotoxic towards human cancer cell lines. Further studies on the phytochemistry and anticancer of MAL are suggested. Sources of information were PubMed, PubMed Central, ScienceDirect, Google, Google Scholar, J-Stage, PubChem and China National Knowledge Infrastructure.
类黄酮是迄今为止从桑树叶（MAL）中分离出的酚类化合物中最主要的一类。其他类化合物有苯并呋喃、酚酸、生物碱、香豆素、查尔酮和芪。主要的类黄酮有桑酮、桑辛素、桑色醇和桑色酮。其他主要化合物包括桑色素（苯并呋喃）、咖啡酰奎宁酸（酚酸）和桑查尔酮（查尔酮）。MAL 的抗癌特性研究包括提取物或分离化合物的体外和体内细胞毒性。类黄酮、苯并呋喃、查尔酮和生物碱是 MAL 中具有细胞毒性的化合物，已被发现对人类癌细胞系具有细胞毒性。建议进一步研究 MAL 的植物化学和抗癌作用。信息来源包括 PubMed、PubMed Central、ScienceDirect、Google、Google Scholar、J-Stage、PubChem 和中国国家知识基础设施。
