内镜黏膜下剥离术治疗早期原发性肛门直肠恶性黑色素瘤 1 例报告
Early primary anorectal malignant melanoma treated with endoscopic submucosal dissection: a case report.
机构信息
Endoscopy Center, Shanghai East Hospital, Tongji University, Shanghai, China.
Department of Gastroenterology and Hepatology, Jing'an District Central Hospital, Fudan University, Shanghai, China.
出版信息
Int J Colorectal Dis. 2020 May;35(5):959-961. doi: 10.1007/s00384-020-03546-6. Epub 2020 Mar 2.
BACKGROUND
Anorectal malignant melanoma (ARMM) is a rare disease accounting for less than 1% of primary anorectal malignancies. Here we first present a case of early primary anorectal malignant melanoma completely resected by endoscopic submucosal dissection (ESD).
METHODS AND RESULTS
A 43-year-old woman visited our hospital because of suspected anal melanoma found by routine colonoscopy in her local hospital. Following series of tests including CT, MRI, and whole-body PET-CT did not show any evidence of metastasis. The lesion was removed by the method of ESD in en bloc and no delayed bleeding or perforation occurred. The result of histopathologic examinations confirmed to be malignant melanoma. No recurrence or distant metastases were found during follow-up time (the latest follow-up was 2 years after ESD).
CONCLUSION
The present case showed endoscopic submucosal dissection that can be an effective and safe alternative treating early primary anorectal malignant melanoma.
背景
肛门直肠恶性黑色素瘤（ARMM）是一种罕见疾病，占原发性肛门直肠恶性肿瘤的比例不到 1%。本文首次报道了 1 例经内镜黏膜下剥离术（ESD）完全切除的早期原发性肛门直肠恶性黑色素瘤。
方法与结果
一名 43 岁女性因在当地医院常规结肠镜检查发现疑似肛门黑色素瘤而就诊。一系列检查包括 CT、MRI 和全身 PET-CT 均未发现转移的证据。病变采用 ESD 整块切除，无延迟性出血或穿孔。病理检查结果证实为恶性黑色素瘤。随访期间未发现复发或远处转移（ESD 后随访时间最长为 2 年）。
结论
本病例显示内镜黏膜下剥离术可作为治疗早期原发性肛门直肠恶性黑色素瘤的有效且安全的替代方法。
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