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儿童急性阑尾炎的腹腔镜与开腹阑尾切除术:一项关于术后结局的全国性回顾性研究

Laparoscopic Versus Open Appendectomy for Acute Appendicitis in Children: a Nationwide Retrospective Study on Postoperative Outcomes.

作者信息

Fujishiro Jun, Watanabe Eiichiro, Hirahara Norimichi, Terui Keita, Tomita Hirofumi, Ishimaru Tetsuya, Miyata Hiroaki

机构信息

Department of Pediatric Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Former Database committee, The Japanese Society of Pediatric Surgeons, Yunizo Urban Koishikawa Bldg. 4F, Otsuka 5-3-13, Bunkyo-ku, Tokyo, 112-0012, Japan.

出版信息

J Gastrointest Surg. 2021 Apr;25(4):1036-1044. doi: 10.1007/s11605-020-04544-3. Epub 2020 Mar 3.

Abstract

PURPOSE

Our aim was to compare postoperative outcomes of laparoscopic and open appendectomies for acute appendicitis in children under the circumstance of widespread use of laparoscopic surgery.

METHOD

This study included data on laparoscopic and open appendectomies in children with acute appendicitis from the National Clinical Database, which is a Japanese nationwide surgical database, in 2015. The occurrence rates of complications within 30 days after the surgery and postoperative hospital stay were compared by univariate and multivariate analyses. p < 0.05 was considered statistically significant.

RESULTS

This study included 4489 appendectomies, of which 3166 surgeries (70.5%) were performed laparoscopically. Appendectomy was performed for complicated and uncomplicated appendicitis in 1765 (39.3%) and 2724 cases (60.7%), respectively. Postoperative complications within 30 days were observed in 246 operations (5.5%). Organ-space surgical site infection (SSI), deep wound SSIs, and superficial wound SSIs were observed in 2.3%, 1.0%, and 2.4% of operations, respectively. On multivariate analysis, the incidence of postoperative complications (odds ratio 1.21, 95% CI 0.90-1.64, p = 0.207) and the length of hospital stay (median 4 days in both groups, p = 0.835) were not significantly different between patients who underwent laparoscopic or open appendectomy. Subgroup analysis in complicated and uncomplicated appendicitis cases also demonstrated no significant differences in the incidence of postoperative complications between those who underwent laparoscopic or open appendectomy.

CONCLUSION

This study suggested that the occurrence of postoperative complication and the length of hospital stay in pediatric patients who underwent laparoscopic appendectomy are similar with those in pediatric patients who underwent open appendectomy for acute appendicitis.

摘要

目的

我们的目的是在腹腔镜手术广泛应用的情况下,比较儿童急性阑尾炎腹腔镜阑尾切除术和开腹阑尾切除术的术后结局。

方法

本研究纳入了2015年来自日本全国性外科数据库国家临床数据库中儿童急性阑尾炎腹腔镜和开腹阑尾切除术的数据。通过单因素和多因素分析比较术后30天内并发症的发生率和术后住院时间。p < 0.05被认为具有统计学意义。

结果

本研究包括4489例阑尾切除术,其中3166例手术(70.5%)为腹腔镜手术。复杂性阑尾炎和非复杂性阑尾炎分别进行了1765例(39.3%)和2724例(60.7%)阑尾切除术。246例手术(5.5%)观察到术后30天内出现并发症。器官腔隙手术部位感染(SSI)、深部伤口SSI和浅表伤口SSI分别在2.3%、1.0%和2.4%的手术中观察到。多因素分析显示,接受腹腔镜或开腹阑尾切除术的患者术后并发症发生率(比值比1.21,95%可信区间0.90 - 1.64,p = 0.207)和住院时间(两组中位数均为4天,p = 0.835)无显著差异。复杂性和非复杂性阑尾炎病例的亚组分析也显示,接受腹腔镜或开腹阑尾切除术的患者术后并发症发生率无显著差异。

结论

本研究表明,儿童急性阑尾炎接受腹腔镜阑尾切除术的术后并发症发生率和住院时间与接受开腹阑尾切除术的儿童相似。

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