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[丹麦丙型肝炎病毒的消除情况]

[Elimination of hepatitis C virus in Denmark].

作者信息

Døssing Anna, Røge Birgitte Thorup, Madsen Lone Galmstrup, Laursen Alex Lund, Hansen Jesper Bach, Bukh Jens, Weis Nina

出版信息

Ugeskr Laeger. 2020 Feb 24;182(9).

Abstract

In Denmark, about 50% of patients with chronic hepatitis C virus (HCV) infection are undiagnosed. Since 2014, therapy containing direct-acting antivirals (DAA) has proven efficient and is available to all patients, who have a chronic HCV infection and a Danish personal identification number. The World Health Organization has a goal of elimination of viral hepatitis in 2030. Elimination of HCV in Denmark should focus on reducing HCV transmission, incidence and prevalence, combined with treatment with DAA of all infected patients. Micro-elimination strategies may play a major role, but a national strategy is lacking.

摘要

在丹麦,约50%的慢性丙型肝炎病毒(HCV)感染患者未被诊断出来。自2014年以来,含直接抗病毒药物(DAA)的疗法已被证明有效,且所有患有慢性HCV感染并拥有丹麦个人身份识别号码的患者均可使用。世界卫生组织的目标是在2030年消除病毒性肝炎。丹麦消除HCV应侧重于减少HCV传播、发病率和患病率,同时对所有感染患者采用DAA治疗。微观消除策略可能发挥重要作用,但目前缺乏国家战略。

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