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杂交腹腔镜胰十二指肠切除术:澳大利亚的经验及实施建议流程

Hybrid laparoscopic pancreaticoduodenectomy: an Australian experience and a proposed process for implementation.

作者信息

Pham Helen, Nahm Christopher B, Hollands Michael, Pang Tony, Johnston Emma, Pleass Henry, Richardson Arthur, Lam Vincent, Yuen Lawrence

机构信息

Department of Hepato-Biliary Pancreatic/Upper Gastrointestinal Surgery, Westmead Hospital, Sydney, New South Wales, Australia.

Faculty of Medical and Health Sciences, Western Clinical School, The University of Sydney, Sydney, New South Wales, Australia.

出版信息

ANZ J Surg. 2020 Jul;90(7-8):1422-1427. doi: 10.1111/ans.15802. Epub 2020 Mar 6.

Abstract

BACKGROUND

Laparoscopic pancreaticoduodenectomy (LPD) is gaining interest with several series reporting favourable outcomes. However, there are significant limitations to the successful implementation of LPD programmes in Australian and New Zealand (ANZ) settings. This study presents a local series of consecutive hybrid LPD (HLPD) and a suggested protocol for implementation of an LPD programme in ANZ settings.

METHODS

A retrospective review of consecutive patients undergoing HLPD with a laparoscopic resection and open reconstruction performed by a single surgeon at two centres in Sydney, Australia, between February 2014 and October 2019 was undertaken. Data were collected from a prospectively maintained database and patient records.

RESULTS

Eighteen patients underwent HLPD. Median operative time was 370 min, with a median laparoscopic resection time of 253 min. Median length of stay was 11 days. There was no mortality within 90 days. Post-operative complications included two patients requiring a return to operating theatre for post-operative pancreatic fistula, and five patients with delayed gastric emptying. Median number of lymph nodes harvested was 13 (interquartile range 11-15.8). Resection margins were negative in 15 patients (83.3%).

CONCLUSION

HLPD is associated with satisfactory perioperative outcomes and may be feasible as a first step towards eventual implementation of LPD in ANZ hospitals.

摘要

背景

腹腔镜胰十二指肠切除术(LPD)正受到越来越多的关注,有多个系列报道了良好的手术结果。然而,在澳大利亚和新西兰(ANZ)地区成功开展LPD项目存在重大限制。本研究展示了一系列本地连续进行的杂交LPD(HLPD)病例,并提出了在ANZ地区实施LPD项目的建议方案。

方法

对2014年2月至2019年10月期间在澳大利亚悉尼的两个中心由同一外科医生进行腹腔镜切除和开放重建的连续HLPD患者进行回顾性研究。数据从前瞻性维护的数据库和患者记录中收集。

结果

18例患者接受了HLPD。中位手术时间为370分钟,中位腹腔镜切除时间为253分钟。中位住院时间为11天。90天内无死亡病例。术后并发症包括2例因术后胰瘘需返回手术室的患者,以及5例胃排空延迟的患者。中位淋巴结清扫数为13个(四分位间距为11 - 15.8)。15例患者(83.3%)的切缘阴性。

结论

HLPD与令人满意的围手术期结果相关,作为ANZ医院最终实施LPD的第一步可能是可行的。

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