用于控制糖尿病患者糖化血红蛋白（HbA1c）水平的智能手机及应用程序：一项系统评价与荟萃分析
Smartphones and Apps to Control Glycosylated Hemoglobin (HbA1c) Level in Diabetes: A Systematic Review and Meta-Analysis.
作者信息
Martos-Cabrera María Begoña, Velando-Soriano Almudena, Pradas-Hernández Laura, Suleiman-Martos Nora, Cañadas-De la Fuente Guillermo A, Albendín-García Luis, Gómez-Urquiza José L
机构信息
San Cecilio Clinical University Hospital, Andalusian Health Service, Avenida del Conocimiento, s/n, 18016 Granada, Spain.
Benamaurel, Northeast District of Granada, Andalusian Health Service, 18817 Granada, Spain.
出版信息
J Clin Med. 2020 Mar 4;9(3):693. doi: 10.3390/jcm9030693.
INTRODUCTION
Diabetes mellitus is a chronic endocrine-metabolic disease, the evolution of which is closely related to people´s self-control of glycemic levels through nutrition, exercise, and medicines.
AIM
To determine whether smartphone apps can help persons with diabetes to improve their % levels of glycosylated hemoglobin.
METHOD
A systematic review and meta-analysis were done. ProQuest, Pubmed/Medline, and Scopus databases were used. The search equation used was "(Prevention and Control) AND Diabetes Mellitus AND Smartphones". The inclusion criteria applied were clinical trials, conducted in 2014-2019.
RESULTS
n = 18 studies were included in the review. The studies tried different applications to monitor glycemia and support patients to improve glycosylated hemoglobin (HbA1c) levels. More than half of the studies found statistically significant differences in HbA1c in the intervention group compared with the control group. Eleven studies were included in the meta-analysis and the study sample was n = 545 for the experimental group and n = 454 for the control group. The meta-analytic estimation of the HbA1c % level means differences between intervention and control group was statistically significant in favour of the intervention group with a mean difference of -0.37 (-0.58, -0.15. 95% confidence interval).
CONCLUSION
Smartphone apps can help people with diabetes to improve their level of HbA1c, but the clinical impact is low.
引言
糖尿病是一种慢性内分泌代谢疾病，其病情发展与人们通过营养、运动和药物对血糖水平的自我控制密切相关。
目的
确定智能手机应用程序是否有助于糖尿病患者提高糖化血红蛋白水平。
方法
进行了一项系统评价和荟萃分析。使用了ProQuest、Pubmed/Medline和Scopus数据库。所使用的搜索式为“(预防与控制) AND 糖尿病 AND 智能手机”。适用的纳入标准为2014 - 2019年开展的临床试验。
结果
该评价纳入了18项研究。这些研究尝试了不同的应用程序来监测血糖水平并支持患者提高糖化血红蛋白(HbA1c)水平。超过半数的研究发现，干预组的HbA1c水平与对照组相比有统计学显著差异。荟萃分析纳入了11项研究，实验组的研究样本量为n = 545，对照组为n = 454。干预组与对照组HbA1c%水平均值差异的荟萃分析估计具有统计学显著性，有利于干预组，平均差值为-0.37(-0.58, -0.15, 95%置信区间)。
结论
智能手机应用程序可帮助糖尿病患者提高HbA1c水平，但临床影响较小。
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