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纳米技术在检测和控制虫媒疾病方面的最新进展。

Recent Developments in Nanotechnology for Detection and Control of -Borne Diseases.

作者信息

Campos Estefânia Vangelie Ramos, de Oliveira Jhones Luiz, Abrantes Daniele Carvalho, Rogério Carolina Barbára, Bueno Carolina, Miranda Vanessa Regina, Monteiro Renata Aparecida, Fraceto Leonardo Fernandes

机构信息

Human and Natural Sciences Center, Federal University of ABC, Santo André, Brazil.

São Paulo State University-UNESP, Institute of Science and Technology, Sorocaba, Brazil.

出版信息

Front Bioeng Biotechnol. 2020 Feb 20;8:102. doi: 10.3389/fbioe.2020.00102. eCollection 2020.

Abstract

Arboviruses such as yellow fever, dengue, chikungunya and zika are transmitted mainly by the mosquito vector . Especially in the tropics, inefficacy of mosquito control causes arboviruses outbreaks every year, affecting the general population with debilitating effects in infected individuals. Several strategies have been tried to control the proliferation of using physical, biological, and chemical control measures. Other methods are currently under research and development, amongst which the use of nanotechnology has attracted a lot of attention of the researchers in relation to the production of more effective repellents and larvicides with less toxicity, and development of rapid sensors for the detection of virus infections. In this review, the utilization of nano-based formulations on control and diagnosis of mosquito-borne diseases were discussed. We also emphasizes the need for future research for broad commercialization of nano-based formulations in world market aiming a positive impact on public health.

摘要

黄热病、登革热、基孔肯雅热和寨卡等虫媒病毒主要通过蚊虫媒介传播。特别是在热带地区,蚊虫控制措施的无效导致虫媒病毒每年爆发,感染个体出现使人衰弱的症状,影响普通人群。人们尝试了多种策略来控制蚊虫繁殖,包括物理、生物和化学控制措施。目前其他方法正在研发中,其中纳米技术的应用在生产毒性较小的更有效驱蚊剂和杀幼虫剂以及开发用于检测病毒感染的快速传感器方面引起了研究人员的广泛关注。在这篇综述中,讨论了基于纳米的制剂在蚊媒疾病控制和诊断中的应用。我们还强调了未来开展研究以推动基于纳米的制剂在世界市场广泛商业化从而对公共卫生产生积极影响的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da4/7047929/1eeb86478c6f/fbioe-08-00102-g0001.jpg

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