School of Mechanical Engineering and Automation, Northeastern University, No. 3-11, Wenhua Road, Heping District, Shenyang, 110819, China.
School of Mechanical Engineering and Automation, Northeastern University, No. 3-11, Wenhua Road, Heping District, Shenyang, 110819, China.
Comput Methods Programs Biomed. 2020 Aug;192:105441. doi: 10.1016/j.cmpb.2020.105441. Epub 2020 Mar 8.
Non-fusion dynamic stabilization surgery is increasingly popular for treating degenerative lumbar disc disease. However, changes in spine biomechanics after application of posterior dynamic fixation devices during whole-body vibration (WBV) remain unclear. The study aimed to examine the effects of non-fusion dynamic stabilization on biomechanical responses of the implanted lumbar spine to vertical WBV.
By modifying L4-L5 segment of the healthy human L1-sacrum finite element model, single-level disc degeneration, dynamic fixation using the BioFlex system and anterior lumbar interbody fusion (ALIF) with rigid fixation were simulated, respectively. Dynamic responses of stress and strain in the spinal levels for the healthy, degenerated, BioFlex and ALIF models under an axial cyclic loading were investigated and compared.
The results showed that endplate stress at implant level was lower in the BioFlex model than in the degenerated and ALIF models, but stress of the connecting rod in the BioFlex system was greater than that in the rigid fixation system used in the ALIF. Compared with the healthy model, stress and strain responses in terms of disc bulge, annulus stress and nucleus pressure at adjacent levels were decreased in the degenerated, BioFlex and ALIF models, but no obvious difference was observed in these responses among the three models.
This study may be helpful to understand variations in vibration characteristics of the lumbar spine after application of non-fusion dynamic stabilization system.
非融合动态稳定手术越来越多地用于治疗退行性腰椎疾病。然而,在全身振动(WBV)期间应用后路动态固定装置后脊柱生物力学的变化尚不清楚。本研究旨在研究非融合动态稳定对垂直 WBV 植入腰椎生物力学反应的影响。
通过修改健康人 L1-骶骨有限元模型的 L4-L5 节段,分别模拟单节段椎间盘退变、使用 BioFlex 系统的动态固定和刚性固定的前路腰椎间融合(ALIF)。研究和比较了健康、退变、BioFlex 和 ALIF 模型在轴向循环加载下脊柱水平的应力和应变的动态响应。
结果表明,在 BioFlex 模型中,与退变和 ALIF 模型相比,植入物水平的终板应力较低,但 BioFlex 系统中的连杆应力大于 ALIF 中使用的刚性固定系统。与健康模型相比,退变、BioFlex 和 ALIF 模型的椎间盘膨出、环应力和相邻节段核压力的应力和应变响应降低,但这三种模型之间的这些响应没有明显差异。
本研究可能有助于了解非融合动态稳定系统应用后腰椎振动特性的变化。