Aoki Kaoru, Haniu Hisao, Kim Yoong Ahm, Saito Naoto
Physical Therapy Division, School of Health Sciences, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.
Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.
Nanomaterials (Basel). 2020 Mar 20;10(3):562. doi: 10.3390/nano10030562.
There has been an increasing amount of research on regenerative medicine for the treatment of bone defects. Scaffolds are needed for the formation of new bone, and various scaffolding materials have been evaluated for bone regeneration. Materials with pores that allow cells to differentiate into osteocytes are preferred in scaffolds for bone regeneration, and porous materials and fibers are well suited for this application. Electrospinning is an effective method for producing a nanosized fiber by applying a high voltage to the needle tip containing a polymer solution. The use of electrospun nanofibers is being studied in the medical field, and its use as a scaffold for bone regeneration therapy has become a topic of growing interest. In this review, we will introduce the potential use of electrospun nanofiber as a scaffold for bone regenerative medicine with a focus on carbon nanofibers produced by the electrospinning method.
关于用于治疗骨缺损的再生医学的研究越来越多。新骨形成需要支架，并且已经对各种支架材料进行了骨再生评估。具有允许细胞分化为骨细胞的孔隙的材料在用于骨再生的支架中是优选的，多孔材料和纤维非常适合此应用。静电纺丝是通过向含有聚合物溶液的针尖施加高电压来生产纳米纤维的有效方法。静电纺丝纳米纤维在医学领域的应用正在研究中，其作为骨再生治疗支架的用途已成为一个越来越受关注的话题。在这篇综述中，我们将介绍静电纺丝纳米纤维作为骨再生医学支架的潜在用途，重点是通过静电纺丝法生产的碳纳米纤维。
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