Cardiovascular Division, Department of Internal Medicine, MacKay Memorial Hospital, MacKay Medical College, New Taipei City, Taiwan; MacKay Junior College of Medicine, Nursing and Management, Taipei, Taiwan.
Cardiovascular Division, Department of Internal Medicine, MacKay Memorial Hospital, MacKay Medical College, New Taipei City, Taiwan.
J Formos Med Assoc. 2021 Jan;120(1 Pt 1):130-136. doi: 10.1016/j.jfma.2020.03.001. Epub 2020 Apr 2.
BACKGROUND/PURPOSE: The prevalence of young-onset diabetes (YOD) is increasing in Asia, but little is known about the metabolic control, associated complications, or medical behavior in this population. Our aim was to assess the prevalence of young-onset and late-onset type 2 diabetes mellitus (T2DM) and their associated risk factors and medical behaviors in Taiwan.
Data were collected from the National Health Insurance Research Database of Taiwan on 11,244 patients from 2008 to 2013. We classified patients with young-onset diabetes if they were diagnosed before 40 years of age and late-onset diabetes (LOD) if diagnosed at 40 years of age or older. We analyzed the prevalence, medication, and medical behaviors between these groups.
We enrolled 2556 newly diagnosed T2DM patients in 2012. Demographics and comorbidities were recorded from YOD (n = 311) and LOD (n = 2245) patients. Most newly diagnosed patients started with monotherapy and almost half of them with sulfonylurea. The prevalence of YOD in Taiwan is up to 12%. In terms of treatment, 42% of T2DM patients are treated in clinics, 58% in hospital, and 25.2% by an endocrinologist.
Our study highlights the rising trend of YOD in Taiwan. National endeavors are urgently needed for early diagnosis, effective management, and primary prevention of diabetes.
背景/目的:亚洲的青年发病型糖尿病(YOD)患病率正在上升,但对于该人群的代谢控制、相关并发症或医疗行为知之甚少。我们旨在评估台湾青年发病和晚发 2 型糖尿病(T2DM)的患病率及其相关危险因素和医疗行为。
数据来自台湾国家健康保险研究数据库,纳入了 2008 年至 2013 年间的 11244 例患者。我们将发病年龄<40 岁的患者归类为青年发病型糖尿病,发病年龄≥40 岁的患者归类为晚发糖尿病(LOD)。分析了这些患者的患病率、药物治疗和医疗行为。
我们在 2012 年纳入了 2556 例新诊断的 T2DM 患者。记录了 YOD(n=311)和 LOD(n=2245)患者的人口统计学和合并症。大多数新诊断的患者开始接受单药治疗,其中近一半患者使用磺脲类药物。台湾的 YOD 患病率高达 12%。在治疗方面,42%的 T2DM 患者在诊所接受治疗,58%在医院,25.2%由内分泌科医生治疗。
我们的研究强调了台湾 YOD 上升的趋势。迫切需要国家努力进行早期诊断、有效管理和糖尿病的一级预防。