MMWR Morb Mortal Wkly Rep. 2020 Apr 10;69(14):422-426. doi: 10.15585/mmwr.mm6914e4.
As of April 2, 2020, the coronavirus disease 2019 (COVID-19) pandemic has resulted in >890,000 cases and >45,000 deaths worldwide, including 239,279 cases and 5,443 deaths in the United States (1,2). In the United States, 22% of the population is made up of infants, children, and adolescents aged <18 years (children) (3). Data from China suggest that pediatric COVID-19 cases might be less severe than cases in adults and that children might experience different symptoms than do adults (4,5); however, disease characteristics among pediatric patients in the United States have not been described. Data from 149,760 laboratory-confirmed COVID-19 cases in the United States occurring during February 12-April 2, 2020 were analyzed. Among 149,082 (99.6%) reported cases for which age was known, 2,572 (1.7%) were among children aged <18 years. Data were available for a small proportion of patients on many important variables, including symptoms (9.4%), underlying conditions (13%), and hospitalization status (33%). Among those with available information, 73% of pediatric patients had symptoms of fever, cough, or shortness of breath compared with 93% of adults aged 18-64 years during the same period; 5.7% of all pediatric patients, or 20% of those for whom hospitalization status was known, were hospitalized, lower than the percentages hospitalized among all adults aged 18-64 years (10%) or those with known hospitalization status (33%). Three deaths were reported among the pediatric cases included in this analysis. These data support previous findings that children with COVID-19 might not have reported fever or cough as often as do adults (4). Whereas most COVID-19 cases in children are not severe, serious COVID-19 illness resulting in hospitalization still occurs in this age group. Social distancing and everyday preventive behaviors remain important for all age groups as patients with less serious illness and those without symptoms likely play an important role in disease transmission (6,7).
截至 2020 年 4 月 2 日,2019 年冠状病毒病(COVID-19)大流行已在全球导致超过 89 万例病例和超过 4.5 万例死亡,其中包括美国的 239279 例病例和 5443 例死亡(1,2)。在美国,22%的人口由<18 岁的婴儿、儿童和青少年组成(儿童)(3)。来自中国的数据表明,儿科 COVID-19 病例可能不如成人病例严重,而且儿童的症状可能与成人不同(4,5);然而,美国儿科患者的疾病特征尚未描述。对 2020 年 2 月 12 日至 4 月 2 日期间美国 149760 例实验室确诊 COVID-19 病例的数据进行了分析。在报告的年龄已知的 149082 例病例中(99.6%),有 2572 例(1.7%)为<18 岁的儿童。许多重要变量的数据可用于一小部分患者,包括症状(9.4%)、基础疾病(13%)和住院状态(33%)。在有可用信息的患者中,与同期 18-64 岁成年人中 93%相比,73%的儿科患者有发热、咳嗽或呼吸急促的症状;所有儿科患者中 5.7%,或已知住院状态的患者中 20%,住院,低于所有 18-64 岁成年人中住院的百分比(10%)或已知住院状态的患者的百分比(33%)。在本分析中纳入的儿科病例中报告了 3 例死亡。这些数据支持先前的发现,即 COVID-19 患儿可能不像成人那样经常报告发热或咳嗽(4)。虽然大多数 COVID-19 患儿病情不严重,但在该年龄组中仍有严重的 COVID-19 疾病导致住院。社交距离和日常预防行为对所有年龄段的人仍然很重要,因为病情较轻的患者和无症状患者可能在疾病传播中发挥重要作用(6,7)。