Department of Dermatology, Göztepe Training and Research Hospital, İstanbul Medeniyet University, İstanbul, Turkey
Department of Pathology, Göztepe Training and Research Hospital, İstanbul Medeniyet University, İstanbul, Turkey
Turk J Med Sci. 2020 Jun 23;50(4):832-843. doi: 10.3906/sag-2002-126.
BACKGROUND/AIM: Cutaneous adnexal tumors (CAT) are rare tumors originating from the adnexal epithelial parts of the skin. Due to its clinical and histopathological characteristics comparable with other diseases, clinicians and pathologists experience difficulties in its diagnosis.We aimed to reveal the clinical and histopathological characteristics of the retrospectively screened cases and to compare the prediagnoses and histopathological diagnoses of clinicians.
The data of the last 5 years were scanned and patients with histopathological diagnosis of CAT were included in the study.
A total of 65 patients, including 39 female and 26 male patients aged between 8 and 88, were included in the study. The female to male ratio was 1.5, and the mean age of the patients was 46.15 ± 21.8 years. The benign tumor rate was 95.4%, whereas the malignant tumor rate was 4.6%. 38.5% of the tumors were presenting sebaceous, 35.4% of them were presenting follicular, and 18.5% of them were presenting eccrine differentiation. It was most commonly seen in the head-neck region with a rate of 66.1%. When clinical and histopathological prediagnoses were compared, prediagnoses and histopathological diagnoses were compatible in 45% of the cases. Most frequently, it was the basal cell carcinoma, epidermal cyst, and sebaceous hyperplasia identified in preliminary diagnoses.
Cutaneous adnexal tumors are very important, as they can accompany different syndromes and may be malignant. Due to difficulties in its clinical diagnosis, histopathological examination must be performed from suspicious lesions for definitive diagnosis.
背景/目的：皮肤附属器肿瘤（CAT）是一种罕见的起源于皮肤附属器上皮部分的肿瘤。由于其临床和组织病理学特征与其他疾病相似，临床医生和病理学家在诊断时会遇到困难。我们旨在揭示回顾性筛选病例的临床和组织病理学特征，并比较临床医生的术前诊断和组织病理学诊断。
扫描了过去 5 年的数据，将组织病理学诊断为 CAT 的患者纳入研究。
共纳入 65 例患者，其中女性 39 例，男性 26 例，年龄 8 至 88 岁，平均年龄为 46.15 ± 21.8 岁。女性与男性的比例为 1.5，良性肿瘤的发生率为 95.4%，恶性肿瘤的发生率为 4.6%。38.5%的肿瘤呈皮脂腺分化，35.4%的肿瘤呈毛囊分化，18.5%的肿瘤呈小汗腺分化。最常见的部位是头颈部，占 66.1%。当比较临床和组织病理学术前诊断时，45%的病例术前诊断和组织病理学诊断相符。最常见的初步诊断为基底细胞癌、表皮囊肿和皮脂腺增生。
皮肤附属器肿瘤非常重要，因为它们可能伴有不同的综合征且可能是恶性的。由于其临床诊断困难，对于可疑病变必须进行组织病理学检查以明确诊断。
