South Australian Health and Medical Research Institute, Adelaide, SA, 5001, Australia.
CALHN, Royal Adelaide Hospital, Adelaide, SA, 5000, Australia.
BMC Psychol. 2020 Apr 17;8(1):34. doi: 10.1186/s40359-020-00400-w.
Depression and obesity are significant global health concerns that commonly occur together. An integrated group cognitive behavioural therapy program was therefore developed to simultaneously address comorbid depression and obesity.
Twenty-four participants (63% women, mean age 46 years) who screened positively for depression with a body mass index ≥25 were recruited from a self-referred general population sample. The group therapy program (10 two-hour weekly sessions) was examined in a single-arm, before-after pilot trial, conducted in a behavioural health clinic in Adelaide, Australia. Primary outcomes included survey and assessment-based analyses of depression, anxiety, body image, self-esteem, and weight (kg), assessed at four time-points: baseline, post-intervention, three-months and 12-months post program. Eighteen participants (75%) completed the program and all assessments.
Significant improvements in depression, anxiety, self-esteem and body shape concern scores, several quality of life domains, eating behaviours and total physical activity (among others) - but not weight - were observed over the course of the trial.
Results from this pilot trial suggest that combining interventions for depression and obesity may be useful. Further development of the program, particularly regarding the potential for physical health benefits, and a randomised controlled trial, are warranted.
Trial registration: ANZCTR, ACTRN12617001079336, 13 July 2017. Retrospectively registered after date of the first consent (6 July 2017), but before the date of the first intervention session (20 July 2017).
抑郁和肥胖是全球范围内两个重大的健康问题，这两种情况经常同时发生。因此，我们开发了一种综合团体认知行为疗法项目，旨在同时解决共病性抑郁和肥胖问题。
从澳大利亚阿德莱德的一家行为健康诊所的自我推荐的一般人群样本中招募了 24 名参与者（63%为女性，平均年龄 46 岁），这些参与者的抑郁症状用贝克抑郁自评量表（BDI）筛查阳性，且体重指数（BMI）≥25。该团体治疗方案（共 10 次，每周 2 次，每次 2 小时）在澳大利亚阿德莱德的一家行为健康诊所进行了单臂、前后试点试验。主要结果包括四次时间点（基线、干预后、三个月和 12 个月后）基于问卷调查和评估的抑郁、焦虑、身体意象、自尊和体重（kg）的分析。18 名参与者（75%）完成了该方案和所有评估。
在试验过程中，抑郁、焦虑、自尊和身体形状担忧评分、多个生活质量领域、饮食行为和总身体活动（除其他外）显著改善，但体重没有改善。
这项试点试验的结果表明，结合针对抑郁和肥胖的干预措施可能是有用的。需要进一步开发该方案，特别是关于身体健康益处的潜力，以及进行随机对照试验。
试验注册：澳大利亚新西兰临床试验注册中心，ACTRN12617001079336，2017 年 7 月 13 日。在第一次同意（2017 年 7 月 6 日）日期之后，但在第一次干预（2017 年 7 月 20 日）日期之前，对该试验进行了回顾性注册。
