• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Mechanical loading effect to the functional bone adaptation.机械负荷对功能性骨适应的影响。
J Frailty Sarcopenia Falls. 2017 Sep 1;2(3):62-64. eCollection 2017 Sep.
2
Is bone's response to mechanical signals dominated by muscle forces?骨骼对机械信号的响应是否主要由肌肉力量决定?
Med Sci Sports Exerc. 2009 Nov;41(11):2044-9. doi: 10.1249/MSS.0b013e3181a8c702.
3
Mechanotransduction and functional response of the skeleton to physical stress: the mechanisms and mechanics of bone adaptation.骨骼对物理应力的机械转导及功能反应:骨适应性的机制与力学原理
J Orthop Sci. 1998;3(6):346-55. doi: 10.1007/s007760050064.
4
[Developments of the theory of skeletal adaptation to mechanical loading].[骨骼对机械负荷适应理论的发展]
Space Med Med Eng (Beijing). 1999 Jun;12(3):226-30.
5
Expression of muscle anabolic and metabolic factors in mechanically loaded MLO-Y4 osteocytes.机械加载的 MLO-Y4 成骨细胞中肌肉合成代谢和代谢因子的表达。
Am J Physiol Endocrinol Metab. 2012 Feb 15;302(4):E389-95. doi: 10.1152/ajpendo.00320.2011. Epub 2011 Nov 22.
6
Mechanical loading and how it affects bone cells: the role of the osteocyte cytoskeleton in maintaining our skeleton.机械加载及其对骨细胞的影响:骨细胞细胞骨架在维持骨骼健康中的作用。
Eur Cell Mater. 2012 Sep 24;24:278-91. doi: 10.22203/ecm.v024a20.
7
Mechanosensation and transduction in osteocytes.成骨细胞中的机械感觉和转导。
Bone. 2013 Jun;54(2):182-90. doi: 10.1016/j.bone.2012.10.013. Epub 2012 Oct 18.
8
Is bone's response to mechanical signals dominated by gravitational loading?骨骼对机械信号的反应是否主要由重力加载决定?
Med Sci Sports Exerc. 2009 Nov;41(11):2037-43. doi: 10.1249/MSS.0b013e3181a8c6e5.
9
New Strategies for the Prevention and Treatment of Bone Loss - From Mechanical Loading Point of View.防治骨质流失的新策略——从机械加载的角度来看。
Curr Pharm Des. 2017;23(41):6264-6271. doi: 10.2174/1381612823666171108121350.
10
Biological underpinnings of Frost's mechanostat thresholds: the important role of osteocytes.弗罗斯特机械感受器阈值的生物学基础:骨细胞的重要作用。
J Musculoskelet Neuronal Interact. 2010 Jun;10(2):128-35.

引用本文的文献

1
Bone-muscle crosstalk under physiological and pathological conditions.在生理和病理条件下的骨-肌相互作用。
Cell Mol Life Sci. 2024 Jul 27;81(1):310. doi: 10.1007/s00018-024-05331-y.

本文引用的文献

1
Reduced gravitational loading does not account for the skeletal effect of botulinum toxin-induced muscle inhibition suggesting a direct effect of muscle on bone.减少重力负荷并不能解释肉毒毒素诱导的肌肉抑制对骨骼的影响,这表明肌肉对骨骼有直接影响。
Bone. 2013 May;54(1):98-105. doi: 10.1016/j.bone.2013.01.043. Epub 2013 Feb 4.
2
Is bone's response to mechanical signals dominated by muscle forces?骨骼对机械信号的响应是否主要由肌肉力量决定?
Med Sci Sports Exerc. 2009 Nov;41(11):2044-9. doi: 10.1249/MSS.0b013e3181a8c702.
3
Effects of low-repetition jump exercise on osteogenic response in rats.低重复次数跳跃运动对大鼠成骨反应的影响。
J Bone Miner Metab. 2008;26(3):226-30. doi: 10.1007/s00774-007-0812-6. Epub 2008 May 11.
4
Contractile properties of EDL and soleus muscles of myostatin-deficient mice.肌肉生长抑制素缺陷小鼠的趾长伸肌和比目鱼肌的收缩特性。
J Appl Physiol (1985). 2006 Sep;101(3):898-905. doi: 10.1152/japplphysiol.00126.2006. Epub 2006 May 18.
5
Increased muscle mass with myostatin deficiency improves gains in bone strength with exercise.肌肉生长抑制素缺乏导致的肌肉量增加可增强运动对骨骼强度的提升效果。
J Bone Miner Res. 2006 Mar;21(3):477-83. doi: 10.1359/JBMR.051203. Epub 2005 Dec 5.
6
From mechanostat theory to development of the "Functional Muscle-Bone-Unit".从机械应力感受器理论到“功能性肌肉-骨骼单元”的发展
J Musculoskelet Neuronal Interact. 2005 Jul-Sep;5(3):232-8.
7
The relationship between muscle size and bone geometry during growth and in response to exercise.生长过程中以及运动反应下肌肉大小与骨骼几何形态之间的关系。
Bone. 2004 Feb;34(2):281-7. doi: 10.1016/j.bone.2003.11.009.
8
Age, sex, and grip strength determine architectural bone parameters assessed by peripheral quantitative computed tomography (pQCT) at the human radius.年龄、性别和握力决定了通过外周定量计算机断层扫描(pQCT)评估的人体桡骨的骨结构参数。
J Biomech. 2001 Apr;34(4):497-503. doi: 10.1016/s0021-9290(00)00211-6.
9
Femoral morphology and cross-sectional geometry of adult myostatin-deficient mice.成年肌肉生长抑制素缺陷小鼠的股骨形态和横截面几何形状。
Bone. 2000 Sep;27(3):343-9. doi: 10.1016/s8756-3282(00)00339-2.
10
Influence of muscle activity on the forces in the femur: an in vivo study.肌肉活动对股骨受力的影响:一项体内研究。
J Biomech. 1997 Nov-Dec;30(11-12):1101-6. doi: 10.1016/s0021-9290(97)00090-0.

机械负荷对功能性骨适应的影响。

Mechanical loading effect to the functional bone adaptation.

作者信息

Kokkinias Alexander D, Kokkinias Sophianos-Orpheus D

机构信息

Physiotherapist.

Technological Educational Institute of Athens, Faculty of Health and Caring Professions, Department of Physiotherapy, Athens, Greece.

出版信息

J Frailty Sarcopenia Falls. 2017 Sep 1;2(3):62-64. eCollection 2017 Sep.

PMID:32313853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7161930/
Abstract

The loads on skeleton control bone turnover, rates of adapted remodeling and influence growth. Mechanical stimulus detected by osteocytes, is derived from muscle contraction or gravity forces. It is difficult to separate the effect of gravity from muscle contractions at bone mass. A great number of studies show that muscle contractions are present, significant and able to represent the large majority which causes the adaptive bone responses.

摘要

骨骼上的负荷控制着骨转换、适应性重塑的速率并影响生长。骨细胞检测到的机械刺激源自肌肉收缩或重力。在骨量方面,很难将重力的影响与肌肉收缩的影响区分开来。大量研究表明,肌肉收缩是存在的、显著的,并且能够代表引起适应性骨反应的绝大多数因素。