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可可的抗炎和抗伤害感受作用:疼痛治疗未来前景综述

Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain.

作者信息

De Feo Martina, Paladini Antonella, Ferri Claudio, Carducci Augusto, Del Pinto Rita, Varrassi Giustino, Grassi Davide

机构信息

Department of Life, Health, and Environmental Sciences, University of L'Aquila, Viale S Salvatore, Delta 6 Medicina, 67100, L'Aquila, Italy.

出版信息

Pain Ther. 2020 Jun;9(1):231-240. doi: 10.1007/s40122-020-00165-5. Epub 2020 Apr 20.

DOI:10.1007/s40122-020-00165-5
PMID:32314320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7203300/
Abstract

Cocoa has been reported to have medicinal properties. It contains a wide range of phytochemicals, including polyphenols, which have been shown to exert anti-inflammatory and antioxidant actions, and also to have a positive effect on pain. Other components of cocoa might be able to positively influence pain perception through various mechanisms. Despite encouraging results from preclinical studies, there is a lack of evidence of antinociceptive effects of cocoa from clinical trials in humans. Further research is needed to better identify the active principles in cocoa, to understand the underlying mechanisms of action, and to establish efficacy in humans.

摘要

据报道,可可具有药用特性。它含有多种植物化学物质,包括多酚,已证明这些多酚具有抗炎和抗氧化作用,并且对疼痛也有积极影响。可可的其他成分可能通过各种机制对疼痛感知产生积极影响。尽管临床前研究取得了令人鼓舞的结果,但缺乏来自人体临床试验的可可抗伤害感受作用的证据。需要进一步研究以更好地确定可可中的活性成分,了解其潜在作用机制,并确定其对人体的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a4/7203300/1a4b8d65a498/40122_2020_165_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a4/7203300/1a4b8d65a498/40122_2020_165_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6a4/7203300/1a4b8d65a498/40122_2020_165_Fig1_HTML.jpg

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