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沙特阿拉伯东部省患有合并症的成年人骨质疏松性骨折的患病率及危险因素

Prevalence and risk factors for osteoporotic fracture among adults with comorbidities in Al-Ahsaa, Saudi Arabia.

作者信息

Al Hamam Naif M, Al-Moaibed Ghusoon F, Alfayez Emad H, Alfayez Eman H, Al-Mubaddil Mohammed Saud, Alramadhan Narjes Ali

机构信息

Orthopedic Consultant, College of Medicine, King Faisal University, Al Ahsaa City, Saudi Arabia.

Medical Intern, College of Medicine, King Faisal University, Al Ahsaa City, Saudi Arabia.

出版信息

J Family Med Prim Care. 2020 Feb 28;9(2):877-882. doi: 10.4103/jfmpc.jfmpc_982_19. eCollection 2020 Feb.

Abstract

BACKGROUND AND AIMS

Little is known about the prevalence of osteoporotic fracture, its sociodemographic correlates, and its comorbid conditions among the adult population of the Kingdome of Saudi Arabia (KSA). Hence, the present work aimed to assess the prevalence of adults at high risk of osteoporotic fracture in the presence of its known risk factors. As well, to determine the most commonly associated comorbidities of osteoporosis in Saudi Arabia.

METHODS

A cross-sectional study was performed among 518 Saudi adults aged over 45 years in Al-Ahsaa city, KSA. The Arabic version of the fracture risk assessment FRAX without bone mineral density (BMD) was presented in an online questionnaire.

RESULTS

The 10-year risk for major osteoporotic fracture was found in 50.81% of the participants; 23.48% of them were at high risk and 25.71% at moderate risk. Also, 26.27% of the respondents were at high risk of hip fracture. Significant correlates of osteoporotic fractures included female gender ( = 0.003), old age ( = 0.000), age at menopause ( = 0.000), low body mass index (BMI; = 0.000), previous fracture ( = 0.000), alcohol consumption ( = 0.000), positive family history ( = 0.000), corticosteroids ( = 0.000), rheumatoid arthritis ( = 0.000), thyroid hyperactivity ( = 0.000), gonadal insufficiency ( = 0.000), chronic liver disease ( = 0.000), nutritional, or gestational disease ( = 0.000).

CONCLUSION

More than a third of the surveyed population had osteoporosis, which was associated with many sociodemographic and clinical characteristics. Therefore, early interventions for osteoporosis and the prevention of other comorbidities may improve the outcome of osteoporosis.

摘要

背景与目的

关于沙特阿拉伯王国(KSA)成年人群中骨质疏松性骨折的患病率、其社会人口学相关因素及其合并症,人们了解甚少。因此,本研究旨在评估存在已知风险因素时骨质疏松性骨折高危成年人的患病率。同时,确定沙特阿拉伯骨质疏松症最常见的相关合并症。

方法

在沙特阿拉伯王国阿哈萨市对518名45岁以上的沙特成年人进行了一项横断面研究。在在线问卷中呈现了不包含骨密度(BMD)的骨折风险评估FRAX阿拉伯语版本。

结果

50.81%的参与者存在10年主要骨质疏松性骨折风险;其中23.48%为高危,25.71%为中危。此外,26.27%的受访者存在髋部骨折高危风险。骨质疏松性骨折的显著相关因素包括女性性别(=0.003)、老年(=0.000)、绝经年龄(=0.000)、低体重指数(BMI;=0.000)、既往骨折(=0.000)、饮酒(=0.000)、阳性家族史(=0.000)、皮质类固醇(=0.000)、类风湿性关节炎(=0.000)、甲状腺功能亢进(=0.000)、性腺功能不全(=0.000)、慢性肝病(=0.000)、营养或妊娠疾病(=0.000)。

结论

超过三分之一的被调查人群患有骨质疏松症,这与许多社会人口学和临床特征相关。因此,对骨质疏松症进行早期干预并预防其他合并症可能会改善骨质疏松症的预后。

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