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[面神经运动诱发电位在前庭神经鞘瘤手术中预测面神经功能的作用]

[The role of facial nerve motor evoked potentials in predicting facial nerve function in vestibular schwannoma surgery].

作者信息

Hong J, Han L, Chen B D, Yao X, Yang Y S

机构信息

Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin 300350, China.

Department of Electrophysiology, Tianjin Huanhu Hospital, Tianjin 300350, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2020 Apr 28;100(16):1245-1248. doi: 10.3760/cma.j.cn112137-20191104-02390.

Abstract

To analyze the role of facial nerve motor evoked potentials in predicting facial nerve function in vestibular schwannoma surgery. In a retrospective clinical study of 226 patients with acoustic neuroma, admitted to our hospital from January 2016 to May 2019, were investigated by facial nerve motor evoked potentials (FNMEP) elicited by multi-pulse transcranial electrical motor cortex stimulation from. For recording the same electrode set-up was used as for continuous EMG monitoring of the orbicularis oculi,oris muscles and mentalis. Pre-surgical (opening dural), intraoperative and post-surgical (closing dural) FNMEP amplitudes and latencies were recorded. End (closing dura) to start (opening dura) amplitude ratios were compared to early-term(3 day after surgery) facial nerve function by House-Brackmann(HB) Grading. 201 patients(88.9%) get a total tumor resection, 15 patients (6.6%) were a subtotal resection, 10 patients(4.4%) were a partial resection. 100 percent of patients had a integrated anatomical preservation of facial nerves, there were four (1.8%) death cases in this group. Reliable FNMEPs were obtained in all patients. The ratio of end-operative to start-operative FNMEP-amplitude showed a negative correlation with early facial nerve function. Correlation was especially close with early function: an amplitude preservation rate of 85.3% led to HB Ⅰ or Ⅱ in 190(84.1%) patients, of 45.6% to HB Ⅲ in 17(7.5%) patients, of 23.1% to HB Ⅳ in 13(5.8%) patients and of 6.7% to HB Ⅴor Ⅵ in 6(2.7%) patients. There was a negative correlation between FNMEP amplitude ratio and post-surgical early HB grading(-0.895, 0.000). FNMEP was highly reliable in predicting early postoperative facial function of the resection of vestibular schwannoma, was a valid protection technique of facial nerve.

摘要

分析面神经运动诱发电位在前庭神经鞘瘤手术中预测面神经功能的作用。在一项对2016年1月至2019年5月我院收治的226例听神经瘤患者的回顾性临床研究中,采用多脉冲经颅电刺激运动皮层引出的面神经运动诱发电位(FNMEP)进行研究。记录时使用与眼轮匝肌、口轮匝肌和颏肌连续肌电图监测相同的电极设置。记录术前(打开硬脑膜)、术中及术后(关闭硬脑膜)的FNMEP波幅和潜伏期。将结束(关闭硬脑膜)至开始(打开硬脑膜)的波幅比与术后早期(术后3天)采用House-Brackmann(HB)分级的面神经功能进行比较。201例(88.9%)患者实现肿瘤全切,15例(6.6%)患者次全切除,10例(4.4%)患者部分切除。100%的患者面神经获得完整解剖保留,该组有4例(1.8%)死亡病例。所有患者均获得可靠的FNMEP。手术结束时与开始时FNMEP波幅之比与早期面神经功能呈负相关。与早期功能的相关性尤为密切:波幅保留率为85.3%时,190例(84.1%)患者达到HBⅠ或Ⅱ级;波幅保留率为45.6%时,17例(7.5%)患者达到HBⅢ级;波幅保留率为23.1%时,13例(5.8%)患者达到HBⅣ级;波幅保留率为6.7%时,6例(2.7%)患者达到HBⅤ或Ⅵ级。FNMEP波幅比与术后早期HB分级呈负相关(-0.895,0.000)。FNMEP在预测前庭神经鞘瘤切除术后早期面部功能方面高度可靠,是一种有效的面神经保护技术。

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