默克尔细胞癌患者的治疗与诊断多学科路径
A Therapeutic and Diagnostic Multidisciplinary Pathway for Merkel Cell Carcinoma Patients.
作者信息
Rastrelli Marco, Del Fiore Paolo, Buja Alessandra, Vecchiato Antonella, Rossi Carlo Riccardo, Chiarion Sileni Vanna, Tropea Saveria, Russano Francesco, Zorzi Manuel, Spina Romina, Cappellesso Rocco, Mazzarotto Renzo, Cavallin Francesco, Bassetto Franco, Bezzon Elisabetta, Ferrazzi Beatrice, Alaibac Mauro, Mocellin Simone
机构信息
Surgical Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Department of Cardiological, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
出版信息
Front Oncol. 2020 Apr 15;10:529. doi: 10.3389/fonc.2020.00529. eCollection 2020.
Merkel Cell Carcinoma (MCC) is a highly aggressive neuroendocrine neoplasm of the skin. Due to its rarity, the management of MCC is not standardized across centers. In this article, we present the experience of the Veneto region in the North-East of Italy, where a committee of skin cancer experts has proposed a clinical pathway for the diagnosis and treatment of MCC. Putting together the evidence available in the international literature, we outlined the best approach to the management of patients affected with this malignancy step- by- step for each possible clinical situation. Crucial in this pathway is the role of the multidisciplinary team to deal with the lack of robust information on each aspect of the management of this disease.
默克尔细胞癌（MCC）是一种极具侵袭性的皮肤神经内分泌肿瘤。由于其罕见性，各中心对MCC的管理并不规范。在本文中，我们介绍了意大利东北部威尼托地区的经验，该地区的皮肤癌专家委员会提出了一条MCC诊断和治疗的临床路径。综合国际文献中的现有证据，我们针对每种可能的临床情况，逐步概述了治疗这种恶性肿瘤患者的最佳方法。在这条路径中，多学科团队的作用至关重要，因为目前关于该疾病管理各方面的可靠信息匮乏。
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