Abed Hassan, Abuljadayel Jameel
Department of Basic and Clinical Oral Sciences, Faculty of Dentistry, Umm Al-Qura University, Makkah, Saudi Arabia.
Department of Sedation and Special Care Dentistry, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.
Spec Care Dentist. 2020 May;40(3):308-314. doi: 10.1111/scd.12463. Epub 2020 May 1.
Factor X deficiency (known as; Stuart-Prower factor deficiency or F10 deficiency) is a rare inherited bleeding disorder. It affects one per 1 million individuals worldwide. Patients with inherited bleeding disorder reported difficulty in accessing primary dental care either due to their medical diseases or their related barriers.
This article aims to identify barriers to oral health as perceived by the patient with factor X deficiency who had been refused treatment by three dentists. A further aim is to provide dentists with the knowledge required to manage patients diagnosed with factor X deficiency.
A 30-year-old male with the inherited, severe factor X deficiency (<1%) was asked to complete a survey which includes 22 semistructured, validated questions to assess his perceived barriers to dental services. Dental examination revealed that the patient required having nonsurgical periodontal therapy under local anesthesia. The treatment plan was discussed with the patient and his hematologist. The patient's hematologist advised performing dental treatment shortly (ie, 1-2 h) after hematological cover with a prothrombin complex concentrate (1000 U; Octoplex ) via intravenous infusion. The hematologist also prescribed tranexamic acid mouthwash (250 mg in 5 mL) and the patient was instructed to rinse his mouth for 3-5 min with 500 μg (10 mL) in case of bleeding following treatment.
The patient reported several barriers to dental services such as high anxiety levels regarding oral bleeding, difficulty in finding a suitable dental clinic, high cost of dental treatment, and the need for hematological cover prior to dental treatment.
The proper communication between dentist and hematologist was a vital step to render safe and effective dental care and to reduce the patient's anxiety toward the dentist.
因子X缺乏症(又称;斯图尔特-普罗沃因子缺乏症或F10缺乏症)是一种罕见的遗传性出血性疾病。全球每100万人中就有1人受其影响。患有遗传性出血性疾病的患者报告称,由于他们的疾病或相关障碍,难以获得初级牙科护理。
本文旨在确定被三位牙医拒绝治疗的因子X缺乏症患者所认为的口腔健康障碍。另一个目的是为牙医提供管理被诊断为因子X缺乏症患者所需的知识。
一名30岁患有遗传性严重因子X缺乏症(<1%)的男性被要求完成一项调查,该调查包括22个经过验证的半结构化问题,以评估他所认为的牙科服务障碍。牙科检查显示,该患者需要在局部麻醉下进行非手术牙周治疗。与患者及其血液科医生讨论了治疗方案。患者的血液科医生建议在通过静脉输注凝血酶原复合物浓缩物(1000 U;Octoplex)进行血液覆盖后不久(即1-2小时)进行牙科治疗。血液科医生还开了氨甲环酸漱口水(5毫升含250毫克),并指示患者在治疗后出血时用500微克(10毫升)漱口3-5分钟。
患者报告了牙科服务的几个障碍,如对口腔出血高度焦虑、难以找到合适的牙科诊所、牙科治疗费用高昂以及牙科治疗前需要血液覆盖。
牙医与血液科医生之间的适当沟通是提供安全有效牙科护理以及减轻患者对牙医焦虑的关键一步。