Modeling Sublethal Effects of Chemicals: Application of a Simplified Dynamic Energy Budget Model to Standard Ecotoxicity Data.

To assess ecological risks from chemical exposure, we need tools to extrapolate from the sublethal effects observed in the laboratory under constant exposure to realistic time-varying exposures. Dynamic energy budget (DEB) theory offers a mechanistic modeling approach to describe the entire life history of a single organism and the effects of toxicant exposure. We use a simplified model, which can be wholly calibrated from standard chronic bioassay data. Case studies on standard test organisms ( and ) are presented to demonstrate the calibration procedure, and for the second case, data are available to pseudovalidate model performance. We use these results to highlight gaps and shortcomings in the current state of the science, and we discuss how these can be overcome to maximize the potential of DEB theory in ecological risk assessment.