Adult Intensive Care, Royal Brompton and Harefield NHS Foundation Trust, UK.
Imperial College London, UK.
Eur Heart J Acute Cardiovasc Care. 2020 Apr;9(3):229-238. doi: 10.1177/2048872620924613. Epub 2020 May 7.
The severe acute respiratory syndrome coronavirus 2 pandemic is to date affecting more than a million of patients and is challenging healthcare professionals around the world. Coronavirus disease 2019 may present with a wide range of clinical spectrum and severity, including severe interstitial pneumonia with high prevalence of hypoxic respiratory failure requiring intensive care admission. There has been increasing sharing experience regarding the patient's clinical features over the last weeks which has underlined the need for general guidance on treatment strategies. We summarise the evidence existing in the literature of oxygen and positive pressure treatments in patients at different stages of respiratory failure and over the course of the disease, including environment and ethical issues related to the ongoing coronavirus disease 2019 infection.
严重急性呼吸综合征冠状病毒 2 型大流行迄今为止已影响了超过 100 万患者,给全世界的医疗保健专业人员带来了挑战。2019 年冠状病毒病的临床表现范围广泛,严重程度不一,包括常见的缺氧性呼吸衰竭需要重症监护治疗的间质性肺炎。在过去的几周中,关于患者临床特征的经验分享不断增加,这突显了制定一般治疗策略的必要性。我们总结了文献中关于不同阶段呼吸衰竭患者和疾病过程中氧疗和正压通气治疗的证据,包括与正在进行的 2019 年冠状病毒病感染相关的环境和伦理问题。