Department of Anatomic Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA.
Head Neck Pathol. 2020 Dec;14(4):1032-1035. doi: 10.1007/s12105-020-01167-7. Epub 2020 May 7.
A 47-year-old man presented to the otolaryngology service with complaint of 6 months of intermittent globus sensation. He reported constant throat clearing and subjective lowering of his voice. Flexible nasolaryngoscopy revealed a large pedunculated mass originating from the left vocal process of the arytenoid, lying superior to the vocal fold. The patient was treated conservatively with an anti-reflux regiment and speech language therapy for 2 months, however he noted marginal worsening in voice over the proceeding interval with an increasing raspy quality. He underwent suspension microlaryngoscopy with biopsy. Microscopic examination demonstrated mucosal epithelium with surface ulceration and considerable fibrinoid necrosis, a mixed inflammatory infiltrate, and abundant granulation tissue with reactive endothelial cells. The diagnosis of laryngeal contact ulcer was rendered. The patient was treated with KTP (potassium titanyl phosphate) laser ablation and corticosteroid microinjection; he tolerated the procedures well and on follow-up noted reduced cough, improving voice quality and no residual dysphagia.
一位 47 岁男性因间歇性咽部异物感 6 个月就诊于耳鼻喉科。他诉持续清嗓,自觉声音低沉。软性鼻咽喉镜检查显示一个大的有蒂肿块源于左侧杓状软骨的声带突,位于声带上方。患者接受了抗反流药物治疗和语言治疗 2 个月,但在随后的随访中他注意到声音略有恶化,声音变得更加嘶哑。他接受了悬雍垂显微镜检查和活检。显微镜检查显示黏膜上皮表面溃疡和大量纤维蛋白样坏死,混合性炎症浸润,以及丰富的肉芽组织和反应性内皮细胞。诊断为喉接触性溃疡。患者接受了 KTP(掺钛钾 磷酸二氢钾)激光消融和皮质类固醇微注射治疗;他耐受良好,随访时咳嗽减少,声音质量改善,无残留吞咽困难。