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肝细胞癌合并梗阻性黄疸患者使用金属支架与塑料支架进行胆道引流的成本分析

Cost Analysis of Biliary Drainage Using Metal versus Plastic Stents in Hepatocellular Carcinoma Patients with Obstructive Jaundice.

作者信息

Elshimi Esam, Morad Wesam

机构信息

Hepatology Department, National Liver Institute, Menoufia University, Shebin Al-Kom, Egypt.

Epidemiology and Preventive Medicine Department, National Liver Institute, Menoufia University, Shebin Al-Kom, Egypt.

出版信息

Gastrointest Tumors. 2020 Apr;7(1-2):1-10. doi: 10.1159/000503862. Epub 2019 Nov 1.

Abstract

BACKGROUND

The optimal method of biliary drainage for biliary obstruction caused by hepatocellular carcinoma (HCC) is controversial, and the possible endoscopic application of plastic and metal stents is the least invasive procedure to improve patients' quality of life.

AIM

Our objective was to study cost evaluation based on a clinical efficacy of both procedures in a randomized trial comparing both approaches in patients with biliary obstruction caused by HCC.

METHODS

The strategy of management was based on clinical effectiveness of biliary drainage with either metal or plastic stents in 90 patients over a 1-year follow-up period. Total (direct and indirect) costs were evaluated.

RESULTS

The direct costs were EGP 40,857.84 and 21,802.62 per patient with plastic and metal stents, respectively. Concerning the indirect costs, EGP 888 and 454 were spent for each patient with plastic and metal stents, respectively. The differences in the costs resulted from patients with plastic stent insertion requiring more second endoscopic retrograde cholangiopancreatography procedures and more medication, medical consultation, and hospitalization during the year of follow-up.

CONCLUSIONS

Based on this analysis, the use of metal stents rather than plastic stents in biliary drainage is more cost effective for this group of patients.

摘要

背景

肝细胞癌(HCC)所致胆道梗阻的最佳胆道引流方法存在争议,塑料和金属支架在内镜下的应用可能是改善患者生活质量的侵入性最小的方法。

目的

我们的目标是在一项随机试验中,基于两种方法对HCC所致胆道梗阻患者的临床疗效进行成本评估,比较这两种方法。

方法

管理策略基于90例患者在1年随访期内使用金属或塑料支架进行胆道引流的临床效果。评估了总(直接和间接)成本。

结果

塑料支架和金属支架置入患者的直接成本分别为每位患者40,857.84埃及镑和21,802.62埃及镑。关于间接成本,塑料支架和金属支架置入患者分别花费888埃及镑和454埃及镑。成本差异源于置入塑料支架的患者在随访年度需要更多的第二次内镜逆行胰胆管造影术、更多的药物、医疗咨询和住院治疗。

结论

基于该分析,对于这组患者,在胆道引流中使用金属支架而非塑料支架更具成本效益。

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本文引用的文献

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Management of malignant biliary obstruction.恶性胆管梗阻的管理
Tech Vasc Interv Radiol. 2008 Mar;11(1):43-50. doi: 10.1053/j.tvir.2008.05.005.
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Hepatocellular carcinoma presenting with obstructive jaundice.以梗阻性黄疸为表现的肝细胞癌。
ANZ J Surg. 2006 Jul;76(7):631-6. doi: 10.1111/j.1445-2197.2006.03794.x.

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