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Anticoagulant and antiarrhythmic effects of heparin in the treatment of COVID-19 patients.

作者信息

Menezes-Rodrigues Francisco Sandro, Padrão Tavares José Gustavo, Pires de Oliveira Marcelo, Guzella de Carvalho Rafael, Ruggero Errante Paolo, Omar Taha Murched, José Fagundes Djalma, Caricati-Neto Afonso

机构信息

Autonomic and Cardiovascular Pharmacology Lab, Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.

School of Medicine, União Metropolitana para o Desenvolvimento da Educação e da Cultura (UNIME), Lauro de Freitas, Brazil.

出版信息

J Thromb Haemost. 2020 Aug;18(8):2073-2075. doi: 10.1111/jth.14902.

Abstract
摘要

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本文引用的文献

1
Heparin Therapy Improving Hypoxia in COVID-19 Patients - A Case Series.
Front Physiol. 2020 Oct 19;11:573044. doi: 10.3389/fphys.2020.573044. eCollection 2020.
2
Cardiac and arrhythmic complications in patients with COVID-19.
J Cardiovasc Electrophysiol. 2020 May;31(5):1003-1008. doi: 10.1111/jce.14479. Epub 2020 Apr 13.
3
Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy.
J Thromb Haemost. 2020 May;18(5):1094-1099. doi: 10.1111/jth.14817. Epub 2020 Apr 27.
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Straight to the heart: Pleiotropic antiarrhythmic actions of oral anticoagulants.
Pharmacol Res. 2019 Jul;145:104257. doi: 10.1016/j.phrs.2019.104257. Epub 2019 May 2.
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The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin.
Immunity. 2019 Apr 16;50(4):1033-1042.e6. doi: 10.1016/j.immuni.2019.03.003. Epub 2019 Mar 26.
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Heparin Oligosaccharides Have Antiarrhythmic Effect by Accelerating the Sodium-Calcium Exchanger.
Front Cardiovasc Med. 2018 Jun 7;5:67. doi: 10.3389/fcvm.2018.00067. eCollection 2018.
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Mechanisms of drug-induced proarrhythmia in clinical practice.
World J Cardiol. 2013 Jun 26;5(6):175-85. doi: 10.4330/wjc.v5.i6.175.

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