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使用扫频源光学相干断层扫描技术比较高度近视眼中飞秒激光原位角膜磨镶术(FS-LASIK)与可植入式角膜接触镜(ICL)植入术后的脉络膜厚度

Comparison of choroidal thickness in high myopic eyes after FS-LASIK versus implantable collamer lens implantation with swept-source optical coherence tomography.

作者信息

Zhang Jing, He Fang-Lin, Liu Yan, Fan Xian-Qun

机构信息

Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.

Shanghai Key Laboratory of Orbital Disease and Ocular Oncology, Shanghai 200011, China.

出版信息

Int J Ophthalmol. 2020 May 18;13(5):773-781. doi: 10.18240/ijo.2020.05.12. eCollection 2020.

Abstract

AIM

To investigate the changes in choroidal thickness (CT) in high myopic eyes after femtosecond laser-assisted keratomileusis (FS-LASIK) surgery or central hole implantable collamer lens (ICL V4c) implantation using swept-source optical coherence tomography (SS-OCT).

METHODS

We examined the right eyes of 116 patients with high myopia who were candidates for FS-LASIK surgery and ICL implantation. Sixty eyes underwent ICL V4c implantation and 56 eyes were subjected to FS-LASIK surgery. The CT was measured with SS-OCT. All data were recorded preoperatively and 2h, 1wk, 1 and 3mo postoperatively. Other demographic information was collected, including age, sex, uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), spherical equivalent (SE), intraocular pressure (IOP) and axial length (AL).

RESULTS

The UCVA improved in both groups and showed no significant differences between groups. There also were no significant differences between the two groups in postoperative BCVA and SE (=0.581 and 0.203, respectively). The foveal CTs, inner nasal and outer nasal CTs were significantly thicker at 2h postoperatively in both groups (<0.05) but returned to baseline levels in 1wk; after 1mo, no significant differences were found relative to the preoperative values. At 3mo in each group, nine regions showed variations in the CT as compared with preoperative thickening, but only the foveal and nasal area CTs preoperative differences were statistically significant (<0.05). In addition, there was no significant difference in 9 regions of CT between the two groups at all follow-up times (>0.05).

CONCLUSION

The CTs after ICL implantation and FS-LASIK surgery are significantly thicker than those before operation, especially in the foveal and nasal areas, but there is no significant difference between the two methods.

摘要

目的

使用扫频光学相干断层扫描(SS-OCT)研究飞秒激光制瓣准分子原位角膜磨镶术(FS-LASIK)或中央孔型可植入式接触镜(ICL V4c)植入术后高度近视眼中脉络膜厚度(CT)的变化。

方法

我们检查了116例有FS-LASIK手术和ICL植入指征的高度近视患者的右眼。60只眼接受了ICL V4c植入,56只眼接受了FS-LASIK手术。使用SS-OCT测量CT。所有数据均在术前以及术后2小时、1周、1个月和3个月记录。收集了其他人口统计学信息,包括年龄、性别、未矫正视力(UCVA)、最佳矫正视力(BCVA)、等效球镜度(SE)、眼压(IOP)和眼轴长度(AL)。

结果

两组患者的UCVA均有改善,且组间无显著差异。两组术后BCVA和SE也无显著差异(分别为=0.581和0.203)。两组术后2小时中央凹CT、鼻内侧和鼻外侧CT均显著增厚(<0.05),但在1周时恢复至基线水平;1个月后,与术前值相比无显著差异。每组术后3个月时,9个区域的CT与术前增厚情况相比有变化,但只有中央凹和鼻侧区域的术前差异有统计学意义(<0.05)。此外,两组在所有随访时间的9个CT区域均无显著差异(>0.05)。

结论

ICL植入和FS-LASIK手术后的CT明显比手术前厚,尤其是在中央凹和鼻侧区域,但两种方法之间无显著差异。

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