Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium.
Translational Cancer Research Unit, GZA Hospitals Sint-Augustinus, Antwerp, Belgium.
Nat Rev Immunol. 2020 Jul;20(7):389-391. doi: 10.1038/s41577-020-0343-0.
On the basis of emerging evidence from patients with COVID-19, we postulate that endothelial cells are essential contributors to the initiation and propagation of severe COVID-19. Here, we discuss current insights into the link between endothelial cells, viral infection and inflammatory changes and propose novel therapeutic strategies.
基于 COVID-19 患者的新出现证据，我们推测内皮细胞是严重 COVID-19 发病和进展的重要贡献者。在此，我们讨论内皮细胞、病毒感染和炎症变化之间的联系的最新认识，并提出新的治疗策略。
