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重症肌无力患者的视神经脊髓炎:两例病例报告。

Neuromyelitis optica in patients with myasthenia gravis: Two case-reports.

作者信息

Castro-Suarez Sheila, Guevara-Silva Erik, Caparó-Zamalloa César, Cortez Jaqueline, Meza-Vega María

机构信息

Basic Research Center in Dementias and Central Nervous System Demyelinating Diseases, Instituto Nacional de Ciencias Neurológicas, 1271 Ancash Street, Lima 15003. Perú; Atlantic Fellow, Global Brain Health Institute, University of California, San Francisco, CA, USA.

Basic Research Center in Dementias and Central Nervous System Demyelinating Diseases, Instituto Nacional de Ciencias Neurológicas, 1271 Ancash Street, Lima 15003. Perú.

出版信息

Mult Scler Relat Disord. 2020 Aug;43:102173. doi: 10.1016/j.msard.2020.102173. Epub 2020 May 13.

Abstract

Neuromyelitis optica spectrum disorders (NMOSD) and myasthenia gravis (MG) are disorders that affect the central nervous system and the neuromuscular junction respectively. Although both conditions are rare, reports of the coexistence of these two pathologies are increasing worldwide. Rarely, patients with MG develop aggressive forms of neuromyelitis optica (NMO) after thymectomy. Here, we describe two Peruvian patients with the association of MG and NMO.

摘要

视神经脊髓炎谱系障碍(NMOSD)和重症肌无力(MG)分别是影响中枢神经系统和神经肌肉接头的疾病。尽管这两种病症都很罕见,但全球范围内关于这两种病理共存的报道正在增加。很少有重症肌无力患者在胸腺切除术后发展为侵袭性视神经脊髓炎(NMO)。在此,我们描述了两名患有重症肌无力和视神经脊髓炎的秘鲁患者。

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