Israelsen Simone Bastrup, Kristiansen Klaus Tjelle, Hindsberger Bettina, Ulrik Charlotte Suppli, Andersen Ove, Jensen Magnus, Andersen Sten, Rasmussen Christian, Jørgensen Henrik L, Østergaard Christian, Lindhardt Bjarne Ørskov, Kronborg Gitte, Benfield Thomas
Dan Med J. 2020 May 15;67(6):A05200313.
The first case of coronavirus disease 2019 (COVID-19) disease caused by severe acute respiratory syndrome coronavirus-2 occurred in Denmark on 27 February 2020. On 10 March, the first case of COVID-19 pneumonia was admitted to Hvidovre Hospital.
Retrospective case review of individuals 18 years or older who were admitted consecutively to Hvidovre Hospital from 10 March through 23 April 2020.
A total of 175 individuals were admitted with COVID-19 pneumonia. The median age was 71 years, 48.6% were male and 71% had at least one co-morbidity. The most commonly presenting symptoms were dyspnoea, dry cough, and fever. The majority of patients had lymphopenia, elevated liver function tests and C-reactive protein. Nearly two in three presented with multilobar infiltration by chest X-ray. Respiratory failure leading to invasive mechanical ventilation developed in 27 patients (15.4%). By 20 April, 23 of 175 (13.1%) patients remained hospitalised, 43 (24.6%) had died and 109 (62.3%) had been discharged.
The manifestations of COVID-19 at presentation were similar to those seen in other reports. Our population was older, slightly overrepresented by women and had a high level of co-morbidity. COVID-19 admittance was associated with frequent need of intensive care and mechanical ventilation that was associated with a very high mortality.
none.
not relevant.
2020年2月27日,丹麦出现首例由严重急性呼吸综合征冠状病毒2引起的2019冠状病毒病(COVID-19)。3月10日,首例COVID-19肺炎患者入住维德医院。
对2020年3月10日至4月23日连续入住维德医院的18岁及以上患者进行回顾性病例分析。
共有175例患者因COVID-19肺炎入院。中位年龄为71岁,48.6%为男性,71%至少有一种合并症。最常见的症状为呼吸困难、干咳和发热。大多数患者出现淋巴细胞减少、肝功能检查和C反应蛋白升高。近三分之二的患者胸部X线显示多叶浸润。27例患者(15.4%)出现呼吸衰竭并接受有创机械通气。截至4月20日,175例患者中有23例(13.1%)仍住院,43例(24.6%)死亡,109例(62.3%)已出院。
COVID-19的临床表现与其他报告中所见相似。我们的患者群体年龄较大,女性略多,合并症水平较高。COVID-19患者常需重症监护和机械通气,且死亡率极高。
无。
不相关。