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创伤后迟发性严重胸骨骨髓炎:针对一例具有挑战性病例的强大多学科协作及一种新型重建技术

Delayed post-traumatic presentation of severe sternal osteomyelitis: A strong multidisciplinary effort and a novel reconstruction technique for a challenging case.

作者信息

Tamburrini Alessandro, Ahmed Hanad, Talbot Thomas, Harrison Oliver, Khan Mansoor, Tilley Simon, Alzetani Aiman

机构信息

Thoracic Surgery Unit, Southampton University Hospital, UK.

Medical School, Southampton University Hospital, UK.

出版信息

Trauma Case Rep. 2020 May 17;27:100305. doi: 10.1016/j.tcr.2020.100305. eCollection 2020 Jun.

Abstract

Sternal osteomyelitis is a morbid and challenging condition, which can rarely occur after trauma, with no established consensus over best therapeutic options. In this case, a 47-year-old man with history of intravenous drug use presented 11 weeks after a minor blunt chest trauma with a severe necrotizing osteomyelitis involving sternum, muscles, fascia and subcutaneous tissue and positive blood cultures for Methicillin Sensitive . Alongside tailored antibiotic therapy, extensive surgical debridement was performed, leaving a full thickness 3 × 4 cm sternal defect and a large skin defect. After 4 weeks of antibiotics and Vacuum-Assisted-Closure pump, a novel reconstruction technique was utilized, with full collaborations of thoracic surgeons, orthopaedic surgeons and plastic surgeons. An autologous tricortical iliac crest bone graft was harvested and shaped to fit the full-thickness sternal defect, while two titanium sigmoid-shaped clavicle plates were used for internal fixation of the autograft. The large skin defect was covered with a pedicled myocutaneous latissimus dorsi flap. Integrity and stability of the chest wall was fully restored, and infection was completely eradicated. No complications occurred and the patient was well at the 18 months follow-up. To the best of our knowledge, this is the first report on autologous iliac crest bone graft in the treatment of sternal osteomyelitis. In this case, it proved to be a viable therapeutic option, providing good long-term clinical and cosmetic results.

摘要

胸骨骨髓炎是一种严重且具有挑战性的病症,极少在创伤后发生,对于最佳治疗方案尚无定论。在此病例中,一名有静脉吸毒史的47岁男性在轻微钝性胸部创伤11周后就诊,患有严重的坏死性骨髓炎,累及胸骨、肌肉、筋膜和皮下组织,血培养结果显示对甲氧西林敏感。除了进行针对性的抗生素治疗外,还进行了广泛的手术清创,导致出现一个3×4厘米的全层胸骨缺损和一个大面积皮肤缺损。在使用抗生素和负压封闭引流泵4周后,采用了一种新的重建技术,胸外科医生、骨科医生和整形外科医生充分协作。取自体三面皮质髂嵴骨块并塑形以适配全层胸骨缺损,同时使用两块钛制乙状锁骨钢板对自体骨进行内固定。大面积皮肤缺损用带蒂背阔肌肌皮瓣覆盖。胸壁的完整性和稳定性得以完全恢复,感染被彻底根除。未发生并发症,患者在18个月随访时情况良好。据我们所知,这是首例关于自体髂嵴骨移植治疗胸骨骨髓炎的报告。在此病例中,它被证明是一种可行的治疗选择,可提供良好的长期临床和美容效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc25/7236049/60f778b030c4/gr1.jpg

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