Department of Biological and Environmental Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.
Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA.
Arch Virol. 2020 Aug;165(8):1891-1894. doi: 10.1007/s00705-020-04660-0. Epub 2020 May 27.
A Portuguese isolate of Aspergillus fumigatus was found to contain three double-stranded (ds) RNA elements ranging in size from 1.1 to 1.8 kbp and comprising the genome of a strain of Aspergillus fumigatus partitivirus 1 (AfuPV-1) previously thought to contain only the two largest dsRNA elements. The sequence of the smallest dsRNA element is described here, completing the sequence of the AfuPV-1 genome. Sequence analysis of the element revealed an open reading frame encoding a protein of unknown function similar in size and distantly related to elements previously identified in other members of the family Partitiviridae.
一个葡萄牙烟曲霉分离株被发现含有三个双链 (ds) RNA 元件,大小从 1.1 到 1.8 kbp 不等,包含先前认为只含有两个最大 dsRNA 元件的烟曲霉部分病毒 1 (AfuPV-1) 的基因组。本文描述了最小 dsRNA 元件的序列,完成了 AfuPV-1 基因组的序列。该元件的序列分析表明,存在一个开放阅读框,编码一种未知功能的蛋白质,其大小与先前在其他部分病毒科成员中鉴定的元件相似,但亲缘关系较远。