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[木叩定对黏液纤毛转运指标的影响]

[Effect of mukodin on indices of mucociliary transport].

作者信息

Solopov V N, Lunichkina I V, Plisko L F, Kolganova N A

出版信息

Ter Arkh. 1988;60(12):55-7.

PMID:3247655
Abstract

The authors report some data on the assessment of efficacy of mucodin, a modern expectorant. Its effect on the rate of mucociliary transport, rheological properties of sputum was studied in patients with infectious-allergic bronchial asthma. Administration of mucodin improves bronchial clearance promoting normalization of bronchial permeability; a positive time course of viscid-elastic indices of the sputum is noted in comparison with the control group. The drugs make no effect on the adhesive properties of sputum. Probable mechanisms of expectorant action of mucodin are discussed.

摘要

作者报告了一些关于现代祛痰剂木库丁疗效评估的数据。在感染性过敏性支气管哮喘患者中研究了其对黏液纤毛运输速率、痰液流变学特性的影响。使用木库丁可改善支气管清除功能,促进支气管通透性正常化;与对照组相比,痰液黏弹性指标呈现出积极的时间进程。该药物对痰液的黏附特性没有影响。文中还讨论了木库丁祛痰作用的可能机制。

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