Mustafa Abdalla, Rizkallah Nayer N H, Samuel Nehemiah, Balupuri Shlokarth
Sunderland Bariatric Unit, Sunderland Royal Hospital, Sunderland, United Kingdom.
General Surgery Department, Cairo University, Egypt.
Ann Med Surg (Lond). 2020 May 18;55:143-147. doi: 10.1016/j.amsu.2020.04.040. eCollection 2020 Jul.
Most Bariatric units perform Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) and One Anastomosis Gastric Bypass (OAGB) for weight loss and metabolic purposes with satisfactory results and low complication profile.
This study compares LRYGB and OAGB outcomes in a high volume single bariatric unit.
Data was collected prospectively and analysed retrospectively for all LRYGB and OAGB performed between Jan 2014 to Dec 2016. The follow up period was for 2 years. Patients who were lost to follow up or had prior bariatric procedure were excluded. Excess weight loss percentage (EWL %), total weight loss percentage (TWL %) and post-operative complications were compared in both groups.
1268 procedures performed. 113 patients were excluded. At 2 years, for LRYGB and OAGB groups mean TWL % was 31% and 35.4% respectively (P < 0.0001); and mean EWL % was 70.1% and 74.8% respectively (P = 0.0119). Gastroesophageal reflux symptoms were higher in OAGB group 17 (8.5%), with 7 patients needing further surgery, versus 26 (2.7%) in LRYGB (P = 0.0003). There was no difference in incidence of marginal ulcers between LRYGB and OAGB 2.7% vs 5% respectively (P = 0.1115). Internal hernia was seen only in LRYGB patients, 22 (2.2%). There was no significant difference in the re-operation rates following LRYGB 52 (5.4%) and OAGB 16 (8%) (P = 0.1824).
OAGB had superior short-term weight loss and low complications profile. Both procedures demonstrated no difference in either marginal ulcers or re-operation rates. Reflux symptoms have remained a major side effect of OAGB.
大多数减肥手术科室开展腹腔镜Roux-en-Y胃旁路术(LRYGB)和单吻合口胃旁路术(OAGB)以实现减重和改善代谢,效果令人满意,并发症发生率低。
本研究比较了在一个大型单一减肥手术科室中LRYGB和OAGB的手术效果。
前瞻性收集2014年1月至2016年12月期间所有实施LRYGB和OAGB手术的数据,并进行回顾性分析。随访期为2年。排除失访或曾接受过减肥手术的患者。比较两组患者的超重减轻百分比(EWL%)、总体重减轻百分比(TWL%)及术后并发症。
共实施了1268例手术。排除113例患者。在2年时,LRYGB组和OAGB组的平均TWL%分别为31%和35.4%(P<0.0001);平均EWL%分别为70.1%和74.8%(P=0.0119)。OAGB组的胃食管反流症状发生率更高,为17例(8.5%),其中7例患者需要进一步手术,而LRYGB组为26例(2.7%)(P=0.0003)。LRYGB组和OAGB组边缘溃疡的发生率分别为2.7%和5%,无差异(P=0.1115)。内疝仅见于LRYGB患者,有22例(2.2%)。LRYGB组和OAGB组的再次手术率分别为52例(5.4%)和16例(8%),无显著差异(P=0.1824)。
OAGB在短期减重方面更优,并发症发生率低。两种手术在边缘溃疡或再次手术率方面无差异。反流症状仍是OAGB的主要副作用。