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腹腔镜Roux-en-Y胃旁路术与单吻合口(回肠袢)胃旁路术治疗肥胖症的前瞻性比较研究:体重减轻及并发症情况

Laparoscopic Roux-En-Y gastric bypass versus one anastomosis (loop) gastric bypass for obesity: A prospective comparative study of weight loss and complications.

作者信息

Mustafa Abdalla, Rizkallah Nayer N H, Samuel Nehemiah, Balupuri Shlokarth

机构信息

Sunderland Bariatric Unit, Sunderland Royal Hospital, Sunderland, United Kingdom.

General Surgery Department, Cairo University, Egypt.

出版信息

Ann Med Surg (Lond). 2020 May 18;55:143-147. doi: 10.1016/j.amsu.2020.04.040. eCollection 2020 Jul.

Abstract

INTRODUCTION

Most Bariatric units perform Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) and One Anastomosis Gastric Bypass (OAGB) for weight loss and metabolic purposes with satisfactory results and low complication profile.

OBJECTIVES

This study compares LRYGB and OAGB outcomes in a high volume single bariatric unit.

METHODS

Data was collected prospectively and analysed retrospectively for all LRYGB and OAGB performed between Jan 2014 to Dec 2016. The follow up period was for 2 years. Patients who were lost to follow up or had prior bariatric procedure were excluded. Excess weight loss percentage (EWL %), total weight loss percentage (TWL %) and post-operative complications were compared in both groups.

RESULTS

1268 procedures performed. 113 patients were excluded. At 2 years, for LRYGB and OAGB groups mean TWL % was 31% and 35.4% respectively (P < 0.0001); and mean EWL % was 70.1% and 74.8% respectively (P = 0.0119). Gastroesophageal reflux symptoms were higher in OAGB group 17 (8.5%), with 7 patients needing further surgery, versus 26 (2.7%) in LRYGB (P = 0.0003). There was no difference in incidence of marginal ulcers between LRYGB and OAGB 2.7% vs 5% respectively (P = 0.1115). Internal hernia was seen only in LRYGB patients, 22 (2.2%). There was no significant difference in the re-operation rates following LRYGB 52 (5.4%) and OAGB 16 (8%) (P = 0.1824).

CONCLUSION

OAGB had superior short-term weight loss and low complications profile. Both procedures demonstrated no difference in either marginal ulcers or re-operation rates. Reflux symptoms have remained a major side effect of OAGB.

摘要

引言

大多数减肥手术科室开展腹腔镜Roux-en-Y胃旁路术(LRYGB)和单吻合口胃旁路术(OAGB)以实现减重和改善代谢,效果令人满意,并发症发生率低。

目的

本研究比较了在一个大型单一减肥手术科室中LRYGB和OAGB的手术效果。

方法

前瞻性收集2014年1月至2016年12月期间所有实施LRYGB和OAGB手术的数据,并进行回顾性分析。随访期为2年。排除失访或曾接受过减肥手术的患者。比较两组患者的超重减轻百分比(EWL%)、总体重减轻百分比(TWL%)及术后并发症。

结果

共实施了1268例手术。排除113例患者。在2年时,LRYGB组和OAGB组的平均TWL%分别为31%和35.4%(P<0.0001);平均EWL%分别为70.1%和74.8%(P=0.0119)。OAGB组的胃食管反流症状发生率更高,为17例(8.5%),其中7例患者需要进一步手术,而LRYGB组为26例(2.7%)(P=0.0003)。LRYGB组和OAGB组边缘溃疡的发生率分别为2.7%和5%,无差异(P=0.1115)。内疝仅见于LRYGB患者,有22例(2.2%)。LRYGB组和OAGB组的再次手术率分别为52例(5.4%)和16例(8%),无显著差异(P=0.1824)。

结论

OAGB在短期减重方面更优,并发症发生率低。两种手术在边缘溃疡或再次手术率方面无差异。反流症状仍是OAGB的主要副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba26/7251295/2ab56c79b051/gr1.jpg

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